Rita. Fragoso, et.al., Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1., PLoS genetics, 2012, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/22916024

Rita. Fragoso, et.al., Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1., PLoS genetics, 2012, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mirc15<tm1.2Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467793
• Mirc16<tm1.2Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467795
• Mirc16<tm1.1Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467794
• Mirc15<tm1.1Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467792
• Mirc14<tm1.1Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467776
• Mirc14<tm1.2Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467791

class

http://purl.org/net/cito/citesAsAuthority

• Mirc15<tm1.2Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467793
• Mirc16<tm1.2Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467795
• Mirc16<tm1.1Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467794
• Mirc15<tm1.1Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467792
• Mirc14<tm1.1Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467776
• Mirc14<tm1.2Czc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5467791

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased double-positive T cell number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0005092EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• thymus hypoplasia_Mirc14<tm1.1Czc>/Mirc14<tm1.1Czc>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001823EI129P2OlaHsd129S4SvJae129S4SvJaeSororI129P2OlaHsd129S4SvJae129S4SvJaeSorC57BL6Mirc14tm11CzcMirc14tm11CzcGtROSA26Sortm1creERT2TyjGtROSA26SorMirc14tm11CzcGtROSA26SorGtROSA26Sortm1creERT2Tyj
• decreased B cell number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0005017EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• decreased germinal center B cell number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0008178EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• increased marginal zone B cell number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0008181EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• decreased double-positive T cell number_Mirc14<tm1.1Czc>/Mirc14<tm1.1Czc>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005092EI129P2OlaHsd129S4SvJae129S4SvJaeSororI129P2OlaHsd129S4SvJae129S4SvJaeSorC57BL6Mirc14tm11CzcMirc14tm11CzcGtROSA26Sortm1creERT2TyjGtROSA26SorMirc14tm11CzcGtROSA26SorGtROSA26Sortm1creERT2Tyj
• increased CD4-positive, alpha beta T cell number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0008074EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• decreased DN3 thymocyte number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0010134EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• increased tumor latency_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0009828EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc
• increased CD8-positive, alpha-beta T cell number_Mirc16<tm1.2Czc>/Mirc16<tm1.2Czc>
  http://metadb.riken.jp/0008078EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc16tm12CzcMirc16tm12CzcMirc16tm12Czc
• decreased thymocyte number_Mirc14<tm1.2Czc>/Mirc14<tm1.2Czc>
  http://metadb.riken.jp/0000715EI129P2OlaHsd129S1Sv129S4SvJaeSororI129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Mirc14tm12CzcMirc14tm12CzcMirc14tm12Czc