Hu. Huang, et.al., Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling., Nature neuroscience, 2012, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/22941110

Hu. Huang, et.al., Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling., Nature neuroscience, 2012, 15

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rock1<tm1.1Itl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5543630

class

http://purl.org/net/cito/citesAsAuthority

• Rock1<tm1.1Itl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5543630

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased body weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Agrp<tm1(cre)Lowl>/Agrp<+>
  http://metadb.riken.jp/0001260I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlAgrptm1creLowlAgrpAgrpRock1tm11ItlAgrptm1creLowl
• increased body weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>
  http://metadb.riken.jp/0001260I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlRock1tm11Itl
• increased body weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0001260I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• obese_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Agrp<tm1(cre)Lowl>/Agrp<+>
  http://metadb.riken.jp/0001261I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlAgrptm1creLowlAgrpAgrpRock1tm11ItlAgrptm1creLowl
• hypoactivity_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0001402I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased circulating insulin level_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0002079I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
他14件を見る
• abnormal nervous system electrophysiology_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Npy-hrGFP)1Lowl/0,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0002272I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgNpyhrGFP1Lowl0TgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11ItlTgNpyhrGFP1Lowl
• insulin resistance_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0005331I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased circulating leptin level_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0005669I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased epididymal fat pad weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Agrp<tm1(cre)Lowl>/Agrp<+>
  http://metadb.riken.jp/0009288I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlAgrptm1creLowlAgrpAgrpRock1tm11ItlAgrptm1creLowl
• increased epididymal fat pad weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0009288I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased mesenteric fat pad weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Agrp<tm1(cre)Lowl>/Agrp<+>
  http://metadb.riken.jp/0009298I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlAgrptm1creLowlAgrpAgrpRock1tm11ItlAgrptm1creLowl
• increased mesenteric fat pad weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0009298I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased renal fat pad weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Agrp<tm1(cre)Lowl>/Agrp<+>
  http://metadb.riken.jp/0009302I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlAgrptm1creLowlAgrpAgrpRock1tm11ItlAgrptm1creLowl
• increased renal fat pad weight_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0009302I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased total body fat amount_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Agrp<tm1(cre)Lowl>/Agrp<+>
  http://metadb.riken.jp/0010024I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlAgrptm1creLowlAgrpAgrpRock1tm11ItlAgrptm1creLowl
• increased total body fat amount_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>
  http://metadb.riken.jp/0010024I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlRock1tm11Itl
• increased total body fat amount_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0010024I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl
• increased food intake_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>
  http://metadb.riken.jp/0011939I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlRock1tm11Itl
• increased food intake_Rock1<tm1.1Itl>/Rock1<tm1.1Itl>,Tg(Pomc1-cre)16Lowl/0
  http://metadb.riken.jp/0011939I129S4SvJaeSorC57BL6FVBNRock1tm11ItlRock1tm11ItlTgPomc1cre16Lowl0TgPomc1cre16LowlRock1tm11Itl