Vincent. Marion, et.al., BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response., Cell metabolism, 2012, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/22958920

Vincent. Marion, et.al., BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response., Cell metabolism, 2012, 16

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444297

class

http://purl.org/net/cito/citesAsAuthority

• Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444297

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone marrow morphology_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0002397B6CgLepobJLepobLepobLepob
• increased fat cell size_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0006094I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• decreased circulating interleukin-6 level_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0008597I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• decreased circulating tumor necrosis factor level_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0008554I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased circulating leptin level_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0005669I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased adipocyte glucose uptake_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0030016I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased insulin sensitivity_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0002891I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased circulating glucose level_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0005559I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• photoreceptor outer segment degeneration_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0008584I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• thin retinal outer nuclear layer_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0008515I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• abnormal eating behavior_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0001431I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• retinal degeneration_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0001326I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased epididymal fat pad weight_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0009288I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• decreased inflammatory response_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0001876I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• decreased birth body size_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0009703I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• decreased circulating free fatty acid level_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0002702I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased adiponectin level_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0004892I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased fat cell size_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0006094B6CgLepobJLepobLepobLepob
• decreased circulating glucose level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005560B6CgLepobJLepobLepobLepob
• abnormal fat cell morphology_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0009115I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• increased susceptibility to diet-induced obesity_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0005658I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• abnormal bone marrow morphology_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0002397I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar
• obese_Bbs12<tm1.1Vmar>/Bbs12<tm1.1Vmar>
  http://metadb.riken.jp/0001261I129S6SvEvTacC57BL6Bbs12tm11VmarBbs12tm11VmarBbs12tm11Vmar

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone marrow morphology in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006373
• decreased circulating glucose level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010721