Juliette. Martin, et.al., Disruption of the histidine triad nucleotide-binding hint2 gene in mice affects glycemic control and mitochondrial function., Hepatology (Baltimore, Md.), 2013, 57

http://rdf.ncbi.nlm.nih.gov/pubmed/22961760

Juliette. Martin, et.al., Disruption of the histidine triad nucleotide-binding hint2 gene in mice affects glycemic control and mitochondrial function., Hepatology (Baltimore, Md.), 2013, 57

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hint2<tm1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5812013
• Hint2<tm1.1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5812015

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased body weight_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0001260I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• impaired glucose tolerance_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0005293I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal enzyme/coenzyme activity_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0005584I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• hepatic steatosis_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002628I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal hepatocyte physiology_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0010080I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal liver morphology_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0000598I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased circulating leptin level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0005669I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased circulating insulin level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002079I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• decreased circulating glucagon level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002696I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal body temperature homeostasis_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0001777I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• oxidative stress_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0003674I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• decreased circulating triglyceride level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002644I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• decreased noradrenaline level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0012574I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal mitochondrial physiology_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0006036I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased circulating alanine transaminase level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002941I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased liver weight_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002981I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased circulating corticosterone level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0001745I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased adiponectin level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0004892I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased liver triglyceride level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0009355I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal retroperitoneal fat pad morphology_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0005337I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• decreased insulin secretion_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0003059I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal mitochondrion morphology_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0006035I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased circulating serum albumin level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002965I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased circulating cholesterol level_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0005178I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• increased insulin sensitivity_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0002891I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno
• abnormal respiratory electron transport chain_Hint2<tm1.1Geno>/Hint2<tm1.1Geno>
  http://metadb.riken.jp/0010955I129S2SvPasC57BL6JHint2tm11GenoHint2tm11GenoHint2tm11Geno

class

http://purl.org/net/cito/citesAsAuthority

• Hint2<tm1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5812013
• Hint2<tm1.1Geno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5812015