Kwang-Hyun. Baek, et.al., Embryonic demise caused by targeted disruption of a cysteine protease Dub-2., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/22984479

Kwang-Hyun. Baek, et.al., Embryonic demise caused by targeted disruption of a cysteine protease Dub-2., PloS one, 2012, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Usp17lc<tm1Khb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5466162

class

http://purl.org/net/cito/citesAsAuthority

• Usp17lc<tm1Khb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5466162

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased thymus weight_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0004955E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• decreased testis weight_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0004852E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• increased CD4-positive, alpha beta T cell number_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0008074E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• decreased cell proliferation_Usp17lc<tm1Khb>/Usp17lc<tm1Khb>
  http://metadb.riken.jp/0000352E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lctm1KhbUsp17lctm1Khb
• increased CD8-positive, alpha-beta T cell number_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0008078E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• increased B cell number_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0005014E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• increased trophectoderm apoptosis_Usp17lc<tm1Khb>/Usp17lc<tm1Khb>
  http://metadb.riken.jp/0012119E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lctm1KhbUsp17lctm1Khb
• failure of blastocyst to hatch from the zona pellucida_Usp17lc<tm1Khb>/Usp17lc<tm1Khb>
  http://metadb.riken.jp/0003694E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lctm1KhbUsp17lctm1Khb
• embryonic lethality before implantation, complete penetrance_Usp17lc<tm1Khb>/Usp17lc<tm1Khb>
  http://metadb.riken.jp/0011094E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lctm1KhbUsp17lctm1Khb
• asthenozoospermia_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0002675E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• increased body weight_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0001260E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb
• increased embryonic tissue cell apoptosis_Usp17lc<tm1Khb>/Usp17lc<tm1Khb>
  http://metadb.riken.jp/0013504E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lctm1KhbUsp17lctm1Khb
• decreased regulatory T cell number_Usp17lc<tm1Khb>/Usp17lc<+>
  http://metadb.riken.jp/0004974E129Usp17lctm1KhborI129SSvEvC57BL6JUsp17lctm1KhbUsp17lcUsp17lcUsp17lctm1Khb