Simona. Capsoni, et.al., SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease., Journal of Alzheimer's disease : JAD, 2013, 33

http://rdf.ncbi.nlm.nih.gov/pubmed/22986780

Simona. Capsoni, et.al., SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease., Journal of Alzheimer's disease : JAD, 2013, 33

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• amyloid beta deposits_Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0003329I129C57BL6SJLTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatTgCMVIgkvaD11BCat
• abnormal object recognition memory_Sorl1<tm1Tew>/Sorl1<tm1Tew>,Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0001458I129C57BL6SJLSorl1tm1TewSorl1tm1TewTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatSorl1tm1TewTgCMVIgkvaD11BCat
• abnormal cholinergic neuron morphology_Sorl1<tm1Tew>/Sorl1<tm1Tew>
  http://metadb.riken.jp/0001038I129C57BL6SJLSorl1tm1TewSorl1tm1TewSorl1tm1Tew
• tau protein deposits_Sorl1<tm1Tew>/Sorl1<tm1Tew>,Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0004250I129C57BL6SJLSorl1tm1TewSorl1tm1TewTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatSorl1tm1TewTgCMVIgkvaD11BCat
• abnormal object recognition memory_Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0001458I129C57BL6SJLTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatTgCMVIgkvaD11BCat
• abnormal cholinergic neuron morphology_Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0001038I129C57BL6SJLTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatTgCMVIgkvaD11BCat
• impaired spatial learning_Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0012307I129C57BL6SJLTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatTgCMVIgkvaD11BCat
• abnormal object recognition memory_Sorl1<tm1Tew>/Sorl1<tm1Tew>
  http://metadb.riken.jp/0001458I129C57BL6SJLSorl1tm1TewSorl1tm1TewSorl1tm1Tew
• neuron degeneration_Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0003224I129C57BL6SJLTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatTgCMVIgkvaD11BCat
• abnormal cholinergic neuron morphology_Sorl1<tm1Tew>/Sorl1<tm1Tew>,Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0001038I129C57BL6SJLSorl1tm1TewSorl1tm1TewTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatSorl1tm1TewTgCMVIgkvaD11BCat
• tau protein deposits_Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0004250I129C57BL6SJLTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatTgCMVIgkvaD11BCat
• impaired spatial learning_Sorl1<tm1Tew>/Sorl1<tm1Tew>
  http://metadb.riken.jp/0012307I129C57BL6SJLSorl1tm1TewSorl1tm1TewSorl1tm1Tew
• impaired spatial learning_Sorl1<tm1Tew>/Sorl1<tm1Tew>,Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0012307I129C57BL6SJLSorl1tm1TewSorl1tm1TewTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatSorl1tm1TewTgCMVIgkvaD11BCat
• amyloid beta deposits_Sorl1<tm1Tew>/Sorl1<tm1Tew>
  http://metadb.riken.jp/0003329I129C57BL6SJLSorl1tm1TewSorl1tm1TewSorl1tm1Tew
• amyloid beta deposits_Sorl1<tm1Tew>/Sorl1<tm1Tew>,Tg(CMV-IgkvaD11)BCat/Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/0003329I129C57BL6SJLSorl1tm1TewSorl1tm1TewTgCMVIgkvaD11BCatTgCMVIgkvaD11BCatSorl1tm1TewTgCMVIgkvaD11BCat
• neuron degeneration_Sorl1<tm1Tew>/Sorl1<tm1Tew>
  http://metadb.riken.jp/0003224I129C57BL6SJLSorl1tm1TewSorl1tm1TewSorl1tm1Tew
• tau protein deposits_Sorl1<tm1Tew>/Sorl1<tm1Tew>
  http://metadb.riken.jp/0004250I129C57BL6SJLSorl1tm1TewSorl1tm1TewSorl1tm1Tew