Amber L. Southwell, et.al., A fully humanized transgenic mouse model of Huntington disease., Human molecular genetics, 2013, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23001568

Amber L. Southwell, et.al., A fully humanized transgenic mouse model of Huntington disease., Human molecular genetics, 2013, 22

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal motor capabilities/coordination/movement_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0002066FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• increased body weight_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0001260FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal forebrain morphology_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0000783FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal corpus callosum morphology_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0000780FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal object recognition memory_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0001458FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal depression-related behavior_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0003360FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• impaired spatial learning_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0012307FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• increased thigmotaxis_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0002797FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal striatum morphology_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0004077FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• impaired coordination_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0001405FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• increased stereotypic behavior_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0001409FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay
• abnormal motor learning_Htt<tm1Hay>/Htt<tm1Hay>,Tg(HTT*97Q)IXwy/0,Tg(YAC18)18Hay/Tg(YAC18)18Hay
  http://metadb.riken.jp/0002804FVBCgHtttm1HayTgHTT97QIXwyTgYAC1818HayHtttm1HayHtttm1HayTgHTT97QIXwy0TgYAC1818HayTgYAC1818HayTgYAC1818HayTgHTT97QIXwyHtttm1Hay