Timothy J. Sargeant, et.al., Characterization of inducible models of Tay-Sachs and related disease., PLoS genetics, 2012, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/23028353

Timothy J. Sargeant, et.al., Characterization of inducible models of Tay-Sachs and related disease., PLoS genetics, 2012, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa
  http://metadb.riken.jp/db/mgi_rdf/MGI:5451192
• Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa
  http://metadb.riken.jp/db/mgi_rdf/MGI:5451190

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• bradykinesia_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0005156I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• microgliosis_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0008918I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• abnormal motor capabilities/coordination/movement_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0002066I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• weight loss_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0001263I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• premature death_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• weight loss_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0001263I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• bradykinesia_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0005156I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• impaired limb coordination_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0001524I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• muscle hypertonia_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0004143I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• abnormal brain morphology_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0002152I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• microgliosis_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0008918I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• bradykinesia_Hexb<tm1Rlp>/Hexb<tm1Rlp>
  http://metadb.riken.jp/0005156I129S4SvJaeC57BL6Hexbtm1RlpHexbtm1RlpHexbtm1Rlp
• premature death_Hexb<tm1Rlp>/Hexb<tm1Rlp>
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6Hexbtm1RlpHexbtm1RlpHexbtm1Rlp
• tremors_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0000745I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• premature death_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• muscle hypertonia_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0004143I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• abnormal motor capabilities/coordination/movement_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0002066I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• tremors_Hexb<tm1Rlp>/Hexb<tm1Rlp>
  http://metadb.riken.jp/0000745I129S4SvJaeC57BL6Hexbtm1RlpHexbtm1RlpHexbtm1Rlp
• impaired limb coordination_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0001524I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• weight loss_Hexb<tm1Rlp>/Hexb<tm1Rlp>
  http://metadb.riken.jp/0001263I129S4SvJaeC57BL6Hexbtm1RlpHexbtm1RlpHexbtm1Rlp
• abnormal spinal cord interneuron morphology_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0004100I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa
• abnormal brain morphology_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0002152I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgSYN1tTA2StetOHexbTjsa0Hexbtm1RlpTgSYN1tTA2StetOHexbTjsa
• tremors_Hexb<tm1Rlp>/Hexb<tm1Rlp>,Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
  http://metadb.riken.jp/0000745I129S4SvJaeC57BL6CBAHexbtm1RlpHexbtm1RlpTgHexbtTA2StetOHexbTjsa0Hexbtm1RlpTgHexbtTA2StetOHexbTjsa

class

http://purl.org/net/cito/citesAsAuthority

• Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa
  http://metadb.riken.jp/db/mgi_rdf/MGI:5451192
• Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa
  http://metadb.riken.jp/db/mgi_rdf/MGI:5451190