Kyoung-Jin. Oh, et.al., TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver., PLoS genetics, 2012, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/23028378

Kyoung-Jin. Oh, et.al., TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver., PLoS genetics, 2012, 8

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating glucose level_Tcf7l2<tm1a(EUCOMM)Wtsi>/Tcf7l2<+>
  http://metadb.riken.jp/0005559C57BL6Tcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2Tcf7l2tm1aEUCOMMWtsiTcf7l2
• abnormal hepatocyte physiology_Tcf7l2<tm1a(EUCOMM)Wtsi>/Tcf7l2<+>
  http://metadb.riken.jp/0010080C57BL6Tcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2Tcf7l2tm1aEUCOMMWtsiTcf7l2
• abnormal glucose homeostasis_Tcf7l2<tm1a(EUCOMM)Wtsi>/Tcf7l2<+>
  http://metadb.riken.jp/0002078C57BL6Tcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2Tcf7l2tm1aEUCOMMWtsiTcf7l2
• lethality, complete penetrance_Tcf7l2<tm1a(EUCOMM)Wtsi>/Tcf7l2<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011400C57BL6Tcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsi
• impaired glucose tolerance_Tcf7l2<tm1a(EUCOMM)Wtsi>/Tcf7l2<+>
  http://metadb.riken.jp/0005293C57BL6Tcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2Tcf7l2tm1aEUCOMMWtsiTcf7l2
• abnormal response/metabolism to endogenous compounds_Tcf7l2<tm1a(EUCOMM)Wtsi>/Tcf7l2<+>
  http://metadb.riken.jp/0003638C57BL6Tcf7l2tm1aEUCOMMWtsiTcf7l2tm1aEUCOMMWtsiTcf7l2Tcf7l2tm1aEUCOMMWtsiTcf7l2