Ni. Qiu, et.al., Conditional mesenchymal disruption of pkd1 results in osteopenia and polycystic kidney disease., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/23029375

Ni. Qiu, et.al., Conditional mesenchymal disruption of pkd1 results in osteopenia and polycystic kidney disease., PloS one, 2012, 7

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0000063I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased bone mineralization_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0020137I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• perinatal lethality_Pkd1<tm1Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0002081I129S4SvJaeCD1Pkd1tm1GggPkd1tm2GggTgCol1a1cre1Bek0TgCol1a1cre1BekPkd1tm1GggPkd1tm2Ggg
• renal fibrosis_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0003985I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• postnatal lethality, incomplete penetrance_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0011086I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• polycystic kidney_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0008528I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• abnormal osteoblast physiology_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0005006I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased trabecular bone volume_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0010879I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased trabecular bone volume_Pkd1<tm1Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0010879I129S4SvJaeCD1Pkd1tm1GggPkd1tm2GggTgCol1a1cre1Bek0TgCol1a1cre1BekPkd1tm1GggPkd1tm2Ggg
• decreased compact bone thickness_Pkd1<tm1Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0000135I129S4SvJaeCD1Pkd1tm1GggPkd1tm2GggTgCol1a1cre1Bek0TgCol1a1cre1BekPkd1tm1GggPkd1tm2Ggg
• increased circulating parathyroid hormone level_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0002904I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• abnormal osteoblast physiology_Pkd1<tm2Ggg>/Pkd1<+>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0005006I129S4SvJaeCD1Pkd1tm2GggPkd1TgCol1a1cre1Bek0Pkd1Pkd1tm2GggTgCol1a1cre1Bek
• abnormal osteoblast differentiation_Pkd1<tm2Ggg>/Pkd1<+>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0008395I129S4SvJaeCD1Pkd1tm2GggPkd1TgCol1a1cre1Bek0Pkd1Pkd1tm2GggTgCol1a1cre1Bek
• premature death_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0002083I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• abnormal exocrine pancreas morphology_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0005220I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• abnormal adipose tissue development_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0011167I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• short femur_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0003109I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• abnormal bone mineralization_Pkd1<tm1Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0002896I129S4SvJaeCD1Pkd1tm1GggPkd1tm2GggTgCol1a1cre1Bek0TgCol1a1cre1BekPkd1tm1GggPkd1tm2Ggg
• abnormal circulating mineral level_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0006357I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• abnormal osteoblast differentiation_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0008395I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased bone mineral density_Pkd1<tm2Ggg>/Pkd1<+>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0000063I129S4SvJaeCD1Pkd1tm2GggPkd1TgCol1a1cre1Bek0Pkd1Pkd1tm2GggTgCol1a1cre1Bek
• decreased body weight_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0001262I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased body size_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0001265I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• short femur_Pkd1<tm1Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0003109I129S4SvJaeCD1Pkd1tm1GggPkd1tm2GggTgCol1a1cre1Bek0TgCol1a1cre1BekPkd1tm1GggPkd1tm2Ggg
• decreased compact bone thickness_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0000135I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased bone mineral density_Pkd1<tm1Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0000063I129S4SvJaeCD1Pkd1tm1GggPkd1tm2GggTgCol1a1cre1Bek0TgCol1a1cre1BekPkd1tm1GggPkd1tm2Ggg
• decreased compact bone thickness_Pkd1<tm2Ggg>/Pkd1<+>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0000135I129S4SvJaeCD1Pkd1tm2GggPkd1TgCol1a1cre1Bek0Pkd1Pkd1tm2GggTgCol1a1cre1Bek
• decreased trabecular bone volume_Pkd1<tm2Ggg>/Pkd1<+>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0010879I129S4SvJaeCD1Pkd1tm2GggPkd1TgCol1a1cre1Bek0Pkd1Pkd1tm2GggTgCol1a1cre1Bek
• pancreas cysts_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0003336I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• increased blood urea nitrogen level_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0005565I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek
• decreased bone mineralization_Pkd1<tm2Ggg>/Pkd1<+>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0020137I129S4SvJaeCD1Pkd1tm2GggPkd1TgCol1a1cre1Bek0Pkd1Pkd1tm2GggTgCol1a1cre1Bek
• abnormal bone marrow morphology_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Col1a1-cre)1Bek/0
  http://metadb.riken.jp/0002397I129S4SvJaeCD1Pkd1tm2GggPkd1tm2GggTgCol1a1cre1Bek0Pkd1tm2GggTgCol1a1cre1Bek