Angèle. Nalbandian, et.al., The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/23029473

Angèle. Nalbandian, et.al., The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology., PloS one, 2012, 7

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal sarcomere morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0004090I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• decreased skeletal muscle mass_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0004819I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• gliosis_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0002183I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• centrally nucleated skeletal muscle fibers_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0009404I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• increased variability of skeletal muscle fiber size_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0009403I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• postnatal growth retardation_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0001732I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• skeletal muscle endomysial fibrosis_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0009420I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal limb bone morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0002115I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• decreased grip strength_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0010053I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal brain morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0002152I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• muscle weakness_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000747I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• myopathy_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000751I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• skeletal muscle fiber necrosis_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0009414I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• kyphosis_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000160I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal skeletal muscle fiber morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0003084I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• decreased body weight_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0001262I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal autophagy_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0008260I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• focal hair loss_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000418I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• motor neuron degeneration_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000938I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal heart morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000266I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• increased mitochondrial fission_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0006038I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• postnatal lethality, complete penetrance_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0011085I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal skeletal muscle morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0000759I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• abnormal mitochondrial crista morphology_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0011635I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl
• decreased body size_Vcp<tm1Itl>/Vcp<tm1Itl>
  http://metadb.riken.jp/0001265I129S6SvEvTacVcptm1ItlVcptm1ItlVcptm1Itl