Fiona C. Brown, et.al., ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level., Blood cells, molecules & diseases, 2013, 50

http://rdf.ncbi.nlm.nih.gov/pubmed/23040355

Fiona C. Brown, et.al., ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level., Blood cells, molecules & diseases, 2013, 50

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hbb-b1<Rbc13>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5460881

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased mean corpuscular hemoglobin_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0005562IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• poikilocytosis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002643IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• anisopoikilocytosis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002641IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• leptocytosis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0010175IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• abnormal definitive hematopoiesis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002123IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• anisopoikilocytosis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002641IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• spherocytosis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002812IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• anisocytosis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002642IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• polychromatophilia_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0005097IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• polychromatophilia_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0005097IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• increased spleen red pulp amount_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0008476IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• hypochromic microcytic anemia_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0008388IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• liver hypoplasia_Hbb-b1<Rbc13>/Hbb-b1<Rbc13>
  http://metadb.riken.jp/0000600IBALBcC57BL6Hbbb1Rbc13Hbbb1Rbc13Hbbb1Rbc13
• lethality throughout fetal growth and development, complete penetrance_Hbb-b1<MommeD7>/Hbb-b1<MommeD7>
  http://metadb.riken.jp/0011099IFVBNHbbb1MommeD7Hbbb1MommeD7Hbbb1MommeD7
• anemia_Hbb-b1<MommeD7>/Hbb-b1<tm1Unc>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0001577I129P2OlaHsdFVBNHbbb1MommeD7Hbbb1tm1UncHbbb2tm1UncHbbb2Hbbb1tm1UncHbbb2tm1UncHbbb2Hbbb1MommeD7
• increased erythrocyte clearance_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0010035IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• leptocytosis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0010175IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• hypochromic microcytic anemia_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0008388IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• abnormal liver morphology_Hbb-b1<MommeD7>/Hbb-b1<MommeD7>
  http://metadb.riken.jp/0000598IFVBNHbbb1MommeD7Hbbb1MommeD7Hbbb1MommeD7
• pallor_Hbb-b1<MommeD7>/Hbb-b1<MommeD7>
  http://metadb.riken.jp/0003717IFVBNHbbb1MommeD7Hbbb1MommeD7Hbbb1MommeD7
• poikilocytosis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002643IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• pallor_Hbb-b1<Rbc13>/Hbb-b1<MommeD7>
  http://metadb.riken.jp/0003717IBALBcC57BL6FVBNHbbb1Rbc13Hbbb1MommeD7Hbbb1MommeD7Hbbb1Rbc13
• increased nucleated erythrocyte cell number_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0009395IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• abnormal liver morphology_Hbb-b1<Rbc13>/Hbb-b1<Rbc13>
  http://metadb.riken.jp/0000598IBALBcC57BL6Hbbb1Rbc13Hbbb1Rbc13Hbbb1Rbc13
• increased erythrocyte clearance_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0010035IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• enlarged spleen_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0000691IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• lethality throughout fetal growth and development, complete penetrance_Hbb-b1<Rbc13>/Hbb-b1<Rbc13>
  http://metadb.riken.jp/0011099IBALBcC57BL6Hbbb1Rbc13Hbbb1Rbc13Hbbb1Rbc13
• extramedullary hematopoiesis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0000240IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• lethality throughout fetal growth and development, complete penetrance_Hbb-b1<Rbc13>/Hbb-b1<tm1Unc>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0011099I129P2OlaHsdBALBcC57BL6Hbbb1Rbc13Hbbb1tm1UncHbbb2tm1UncHbbb2Hbbb2Hbbb1Rbc13Hbbb2tm1UncHbbb1tm1Unc
• lethality throughout fetal growth and development, complete penetrance_Hbb-b1<MommeD7>/Hbb-b1<tm1Unc>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0011099I129P2OlaHsdFVBNHbbb1MommeD7Hbbb1tm1UncHbbb2tm1UncHbbb2Hbbb1tm1UncHbbb2tm1UncHbbb2Hbbb1MommeD7
• increased red blood cell distribution width_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0010067IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• anisocytosis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002642IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• increased nucleated erythrocyte cell number_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0009395IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• enlarged spleen_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0000691IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• schistocytosis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0000314IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• pallor_Hbb-b1<Rbc13>/Hbb-b1<Rbc13>
  http://metadb.riken.jp/0003717IBALBcC57BL6Hbbb1Rbc13Hbbb1Rbc13Hbbb1Rbc13
• liver hypoplasia_Hbb-b1<MommeD7>/Hbb-b1<MommeD7>
  http://metadb.riken.jp/0000600IFVBNHbbb1MommeD7Hbbb1MommeD7Hbbb1MommeD7
• increased spleen red pulp amount_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0008476IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• abnormal definitive hematopoiesis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002123IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• extramedullary hematopoiesis_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0000240IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• increased red blood cell distribution width_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0010067IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• decreased mean corpuscular volume_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002591IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• decreased mean corpuscular hemoglobin_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0005562IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• decreased mean corpuscular volume_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002591IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• spherocytosis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002812IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• anemia_Hbb-b1<Rbc13>/Hbb-b1<tm1Unc>,Hbb-b2<tm1Unc>/Hbb-b2<+>
  http://metadb.riken.jp/0001577I129P2OlaHsdBALBcC57BL6Hbbb1Rbc13Hbbb1tm1UncHbbb2tm1UncHbbb2Hbbb2Hbbb1Rbc13Hbbb2tm1UncHbbb1tm1Unc
• schistocytosis_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0000314IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13
• microcytic anemia_Hbb-b1<MommeD7>/Hbb-b1<+>
  http://metadb.riken.jp/0002810IFVBNHbbb1MommeD7Hbbb1Hbbb1MommeD7Hbbb1
• microcytic anemia_Hbb-b1<Rbc13>/Hbb-b1<+>
  http://metadb.riken.jp/0002810IBALBcC57BL6Hbbb1Rbc13Hbbb1Hbbb1Hbbb1Rbc13

class

http://purl.org/net/cito/citesAsAuthority

• Hbb-b1<Rbc13>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5460881