Vasiliki. Koliaraki, et.al., Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis., The Journal of clinical investigation, 2012, 122

http://rdf.ncbi.nlm.nih.gov/pubmed/23064365

Vasiliki. Koliaraki, et.al., Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis., The Journal of clinical investigation, 2012, 122

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Map3k8<tm1.1Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5476710
• Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5476711

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor growth/size_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0003721I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• decreased sensitivity to xenobiotic induced morbidity/mortality_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0009767I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• abnormal enterocyte proliferation_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0008883I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• increased physiological sensitivity to xenobiotic_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0008873I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• decreased colon length_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0013956I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• increased sensitivity to xenobiotic induced morbidity/mortality_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0009766I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• increased incidence of tumors by chemical induction_Map3k8<tm1.1Gkl>/Map3k8<tm1.1Gkl>,Tg(Col6a1-cre)1Gkl/0
  http://metadb.riken.jp/0004499IC57BL6CBAFVBNMap3k8tm11GklMap3k8tm11GklTgCol6a1cre1Gkl0Map3k8tm11GklTgCol6a1cre1Gkl
• decreased tumor necrosis factor secretion_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0008561I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• abnormal colon morphology_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0000495I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• rectal hemorrhage_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0003293I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• diarrhea_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0005036I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• abnormal enterocyte apoptosis_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0008884I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• abnormal colon morphology_Map3k8<tm1.1Gkl>/Map3k8<tm1.1Gkl>,Tg(Col6a1-cre)1Gkl/0
  http://metadb.riken.jp/0000495IC57BL6CBAFVBNMap3k8tm11GklMap3k8tm11GklTgCol6a1cre1Gkl0Map3k8tm11GklTgCol6a1cre1Gkl
• increased susceptibility to weight loss_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0010180I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl
• increased tumor growth/size_Map3k8<tm1.1Gkl>/Map3k8<tm1.1Gkl>,Tg(Col6a1-cre)1Gkl/0
  http://metadb.riken.jp/0003721IC57BL6CBAFVBNMap3k8tm11GklMap3k8tm11GklTgCol6a1cre1Gkl0Map3k8tm11GklTgCol6a1cre1Gkl
• abnormal enterocyte apoptosis_Map3k8<tm1.1Gkl>/Map3k8<tm1.1Gkl>,Tg(Col6a1-cre)1Gkl/0
  http://metadb.riken.jp/0008884IC57BL6CBAFVBNMap3k8tm11GklMap3k8tm11GklTgCol6a1cre1Gkl0Map3k8tm11GklTgCol6a1cre1Gkl
• abnormal enterocyte proliferation_Map3k8<tm1.1Gkl>/Map3k8<tm1.1Gkl>,Tg(Col6a1-cre)1Gkl/0
  http://metadb.riken.jp/0008883IC57BL6CBAFVBNMap3k8tm11GklMap3k8tm11GklTgCol6a1cre1Gkl0Map3k8tm11GklTgCol6a1cre1Gkl
• increased incidence of tumors by chemical induction_Map3k8<tm1.2Gkl>/Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/0004499I129C57BL6JFVBNMap3k8tm12GklMap3k8tm12GklMap3k8tm12Gkl

class

http://purl.org/net/cito/citesAsAuthority

• Map3k8<tm1.1Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5476710
• Map3k8<tm1.2Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5476711