Huimin. Yu, et.al., Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes., Development (Cambridge, England), 2012, 139

http://rdf.ncbi.nlm.nih.gov/pubmed/23095888

Huimin. Yu, et.al., Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes., Development (Cambridge, England), 2012, 139

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ventricular septal defect_Dvl3<tm1Awb>/Dvl3<+>,Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0010402I129C57BL6Dvl3tm1AwbDvl3Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatDvl3tm1AwbFzd2tm11NatDvl3Fzd2Fzd7tm11Nat
• abnormal heart development_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000267I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• abnormal heart morphology_Fzd2<tm1.1Nat>/Fzd2<+>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0000266I129C57BL6LPTLeJFzd2tm11NatFzd2Vangl2LpVangl2Fzd2Fzd2tm11NatVangl2Vangl2Lp
• ventricular septal defect_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0010402I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11NatFzd2
• ventricular septal defect_Dvl3<tm1Awb>/Dvl3<tm1Awb>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0010402I129C57BL6Dvl3tm1AwbDvl3tm1AwbFzd7tm11NatFzd7tm11NatFzd7tm11NatDvl3tm1Awb
• short tail_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt5a<tm1Amc>/Wnt5a<+>
  http://metadb.riken.jp/0000592I129C57BL6Fzd7tm11NatFzd7tm11NatWnt5atm1AmcWnt5aWnt5atm1AmcFzd7tm11NatWnt5a
• abnormal heart morphology_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt3a<tm1Amc>/Wnt3a<+>
  http://metadb.riken.jp/0000266I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt3atm1AmcWnt3aWnt3atm1AmcFzd2Fzd2tm11NatFzd7tm11NatWnt3a
• abnormal heart morphology_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0000266I129C57BL6LPTLeJFzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatVangl2LpVangl2Vangl2Fzd7tm11NatFzd2Fzd2tm11NatVangl2Lp
• embryonic growth retardation_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt5a<tm1Amc>/Wnt5a<+>
  http://metadb.riken.jp/0003984I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt5atm1AmcWnt5aFzd7tm11NatWnt5atm1AmcFzd2Fzd2tm11NatWnt5a
• decreased embryo size_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0001698I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• short tail_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000592I129C57BL6Fzd7tm11NatFzd7tm11NatFzd7tm11Nat
• double outlet right ventricle_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000284I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11NatFzd2
• embryonic lethality during organogenesis, complete penetrance_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0011098I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• ventricular septal defect_Dvl3<tm1Awb>/Dvl3<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0010402I129C57BL6Dvl3tm1AwbDvl3Fzd7tm11NatFzd7tm11NatDvl3tm1AwbDvl3Fzd7tm11Nat
• cleft palate_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0000111I129C57BL6LPTLeJFzd7tm11NatFzd7tm11NatVangl2LpVangl2Fzd7tm11NatVangl2Vangl2Lp
• cleft palate_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000111I129C57BL6LPTLeJFzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatFzd2tm11NatFzd2Fzd7tm11Nat
• ventricular septal defect_Fzd2<tm1.1Nat>/Fzd2<+>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0010402I129C57BL6LPTLeJFzd2tm11NatFzd2Vangl2LpVangl2Fzd2Fzd2tm11NatVangl2Vangl2Lp
• ventricular septal defect_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt3a<tm1Amc>/Wnt3a<+>
  http://metadb.riken.jp/0010402I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt3atm1AmcWnt3aWnt3atm1AmcFzd2Fzd2tm11NatFzd7tm11NatWnt3a
• abnormal heart morphology_Dvl3<tm1Awb>/Dvl3<+>,Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000266I129C57BL6Dvl3tm1AwbDvl3Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatDvl3tm1AwbFzd2tm11NatDvl3Fzd2Fzd7tm11Nat
• abnormal heart morphology_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000266I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11NatFzd2
• abnormal heart morphology_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt11<tm1Amc>/Wnt11<+>
  http://metadb.riken.jp/0000266I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt11tm1AmcWnt11Fzd7tm11NatWnt11tm1AmcFzd2Wnt11Fzd2tm11Nat
• incomplete embryo turning_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0001701I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• abnormal heart morphology_Dvl3<tm1Awb>/Dvl3<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000266I129C57BL6Dvl3tm1AwbDvl3Fzd7tm11NatFzd7tm11NatDvl3tm1AwbDvl3Fzd7tm11Nat
• diluted coat color_Fzd1<tm1.1Nat>/Fzd1<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000371I129C57BL6Fzd1tm11NatFzd1tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd1tm11Nat
• cleft palate_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt3a<tm1Amc>/Wnt3a<+>
  http://metadb.riken.jp/0000111I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt3atm1AmcWnt3aWnt3atm1AmcFzd2Fzd2tm11NatFzd7tm11NatWnt3a
• abnormal embryonic tissue morphology_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0002085I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• disorganized yolk sac vascular plexus_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0001723I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• ventricular septal defect_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0010402I129C57BL6LPTLeJFzd7tm11NatFzd7tm11NatVangl2LpVangl2Fzd7tm11NatVangl2Vangl2Lp
• abnormal heart morphology_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0000266I129C57BL6LPTLeJFzd7tm11NatFzd7tm11NatVangl2LpVangl2Fzd7tm11NatVangl2Vangl2Lp
• ventricular septal defect_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt3a<tm1Amc>/Wnt3a<+>
  http://metadb.riken.jp/0010402I129C57BL6Fzd7tm11NatFzd7tm11NatWnt3atm1AmcWnt3aWnt3aWnt3atm1AmcFzd7tm11Nat
• cleft palate_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>
  http://metadb.riken.jp/0000111I129S1Sv129X1SvJC57BL6Fzd2tm11NatFzd2tm11NatFzd2tm11Nat
• cleft palate_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt11<tm1Amc>/Wnt11<+>
  http://metadb.riken.jp/0000111I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt11tm1AmcWnt11Fzd7tm11NatWnt11tm1AmcFzd2Wnt11Fzd2tm11Nat
• abnormal parietal yolk sac morphology_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0011203I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• ventricular septal defect_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0010402I129C57BL6LPTLeJFzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatVangl2LpVangl2Vangl2Fzd7tm11NatFzd2Fzd2tm11NatVangl2Lp
• cleft palate_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Vangl2<Lp>/Vangl2<+>
  http://metadb.riken.jp/0000111I129C57BL6LPTLeJFzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatVangl2LpVangl2Vangl2Fzd7tm11NatFzd2Fzd2tm11NatVangl2Lp
• open neural tube_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000929I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• decreased angiogenesis_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0005602I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• abnormal heart morphology_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt3a<tm1Amc>/Wnt3a<+>
  http://metadb.riken.jp/0000266I129C57BL6Fzd7tm11NatFzd7tm11NatWnt3atm1AmcWnt3aWnt3aWnt3atm1AmcFzd7tm11Nat
• kinked tail_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000585I129C57BL6Fzd7tm11NatFzd7tm11NatFzd7tm11Nat
• abnormal heart morphology_Dvl3<tm1Awb>/Dvl3<tm1Awb>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000266I129C57BL6Dvl3tm1AwbDvl3tm1AwbFzd7tm11NatFzd7tm11NatFzd7tm11NatDvl3tm1Awb
• ventricular septal defect_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt11<tm1Amc>/Wnt11<+>
  http://metadb.riken.jp/0010402I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt11tm1AmcWnt11Fzd7tm11NatWnt11tm1AmcFzd2Wnt11Fzd2tm11Nat
• embryonic growth retardation_Fzd2<tm1.1Nat>/Fzd2<tm1.1Nat>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0003984I129C57BL6Fzd2tm11NatFzd2tm11NatFzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11Nat
• postnatal lethality, incomplete penetrance_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0011086I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatFzd7tm11NatFzd2tm11NatFzd2
• embryonic lethality during organogenesis, complete penetrance_Fzd2<tm1.1Nat>/Fzd2<+>,Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>,Wnt5a<tm1Amc>/Wnt5a<+>
  http://metadb.riken.jp/0011098I129C57BL6Fzd2tm11NatFzd2Fzd7tm11NatFzd7tm11NatWnt5atm1AmcWnt5aFzd7tm11NatWnt5atm1AmcFzd2Fzd2tm11NatWnt5a
• abnormal heart morphology_Fzd7<tm1.1Nat>/Fzd7<tm1.1Nat>
  http://metadb.riken.jp/0000266I129C57BL6Fzd7tm11NatFzd7tm11NatFzd7tm11Nat