Jennifer J. Hofmann, et.al., Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome., Development (Cambridge, England), 2012, 139

http://rdf.ncbi.nlm.nih.gov/pubmed/23095891

Jennifer J. Hofmann, et.al., Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome., Development (Cambridge, England), 2012, 139

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• calcified aortic valve_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0006116B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• ventricular septal defect_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0010402B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal atrioventricular cushion morphology_Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Cdh5-cre)7Mlia/0,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000297I129129S4SvJaeSorFVBNNotch1tm1AgtNotch1tm1AgtTgCdh5cre7Mlia0GtROSA26Sortm1SorGtROSA26SorNotch1tm1AgtGtROSA26Sortm1SorTgCdh5cre7MliaGtROSA26Sor
• pulmonary valve regurgitation_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0006048B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal coronary vessel morphology_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0010551B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• increased systemic arterial systolic blood pressure_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0006144B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal heart valve morphology_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000285B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• heart right ventricle hypertrophy_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000276B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal heart morphology_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000266B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• pulmonary valve stenosis_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0006128B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• overriding aortic valve_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000273B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal aorta morphology_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000272B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal cardiac epithelial to mesenchymal transition_Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Cdh5-cre)7Mlia/0,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008825I129129S4SvJaeSorFVBNNotch1tm1AgtNotch1tm1AgtTgCdh5cre7Mlia0GtROSA26Sortm1SorGtROSA26SorNotch1tm1AgtGtROSA26Sortm1SorTgCdh5cre7MliaGtROSA26Sor
• abnormal pulmonary trunk morphology_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000486B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• thick heart valve cusps_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0011648B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal cardiac epithelial to mesenchymal transition_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008825I129129S4SvJaeSorFVBNJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0GtROSA26Sortm1SorGtROSA26SorTgCdh5cre7MliaJag1tm1FradGtROSA26SorGtROSA26Sortm1Sor
• increased heart right ventricle size_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0010563B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• enlarged heart right atrium_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0008727B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• thick ventricular wall_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0002953B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal atrioventricular cushion morphology_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000297I129129S4SvJaeSorFVBNJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0GtROSA26Sortm1SorGtROSA26SorTgCdh5cre7MliaJag1tm1FradGtROSA26SorGtROSA26Sortm1Sor
• dilated heart_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0004937B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia
• abnormal cardiac outflow tract development_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0006126B6CgJag1tm1FradTgCdh5cre7MliaJag1tm1FradJag1tm1FradTgCdh5cre7Mlia0Jag1tm1FradTgCdh5cre7Mlia