Isabel. Hidalgo, et.al., Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest., Cell stem cell, 2012, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/23122289

Isabel. Hidalgo, et.al., Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest., Cell stem cell, 2012, 11

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ezh1<tm1Sgon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5474772

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• early cellular replicative senescence_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008008I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• abnormal bone marrow cell physiology_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0009278I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• small spleen_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0000692I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• lymphoid hypoplasia_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0002223I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• abnormal hematopoietic stem cell physiology_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0010763I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased bone marrow cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0000333I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• abnormal myeloid leukocyte morphology_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008250I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• abnormal common lymphocyte progenitor cell morphology_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008249I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased spleen white pulp amount_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008479I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased pro-B cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008208I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased hematopoietic stem cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0004810I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased B cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0005017I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased immature B cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008215I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• absent spleen germinal center_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008474I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon
• decreased spleen red pulp amount_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0
  http://metadb.riken.jp/0008477I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon

class

http://purl.org/net/cito/citesAsAuthority

• Ezh1<tm1Sgon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5474772