Julio C. Ruiz, et.al., F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis., The Journal of biological chemistry, 2013, 288

http://rdf.ncbi.nlm.nih.gov/pubmed/23135277

Julio C. Ruiz, et.al., F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis., The Journal of biological chemistry, 2013, 288

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic growth retardation_Fbxl5<Gt(OST386421)Lex>/Fbxl5<Gt(OST386421)Lex>
  http://metadb.riken.jp/0003984I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5GtOST386421LexFbxl5GtOST386421Lex
• decreased liver iron level_Fbxl5<Gt(OST386421)Lex>/Fbxl5<+>
  http://metadb.riken.jp/0008743I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5Fbxl5Fbxl5GtOST386421Lex
• abnormal erythrocyte morphology_Fbxl5<Gt(OST386421)Lex>/Fbxl5<+>
  http://metadb.riken.jp/0002447I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5Fbxl5Fbxl5GtOST386421Lex
• prenatal lethality, complete penetrance_Aco1<tm1.2Mwh>/Aco1<tm1.2Mwh>,Fbxl5<Gt(OST386421)Lex>/Fbxl5<Gt(OST386421)Lex>
  http://metadb.riken.jp/0011091I129P2OlaHsd129S5SvEvBrdC57BL6Aco1tm12MwhAco1tm12MwhFbxl5GtOST386421LexFbxl5GtOST386421LexFbxl5GtOST386421LexAco1tm12Mwh
• abnormal erythrocyte morphology_Fbxl5<Gt(OST386421)Lex>/Fbxl5<+>
  http://metadb.riken.jp/0002447129SB6Fbxl5GtOST386421LexFbxl5GtOST386421LexFbxl5Fbxl5Fbxl5GtOST386421Lex
• embryonic lethality during organogenesis, complete penetrance_Fbxl5<Gt(OST386421)Lex>/Fbxl5<Gt(OST386421)Lex>
  http://metadb.riken.jp/0011098I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5GtOST386421LexFbxl5GtOST386421Lex
• increased spleen iron level_Fbxl5<Gt(OST386421)Lex>/Fbxl5<+>
  http://metadb.riken.jp/0008809I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5Fbxl5Fbxl5GtOST386421Lex
• anemia_Fbxl5<Gt(OST386421)Lex>/Fbxl5<Gt(OST386421)Lex>,Ireb2<tm1.2Mwh>/Ireb2<tm1.2Mwh>
  http://metadb.riken.jp/0001577I129P2OlaHsd129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5GtOST386421LexIreb2tm12MwhIreb2tm12MwhIreb2tm12MwhFbxl5GtOST386421Lex
• increased intestinal iron level_Fbxl5<Gt(OST386421)Lex>/Fbxl5<+>
  http://metadb.riken.jp/0020369I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5Fbxl5Fbxl5GtOST386421Lex
• abnormal iron homeostasis_Fbxl5<Gt(OST386421)Lex>/Fbxl5<+>
  http://metadb.riken.jp/0005637I129S5SvEvBrdC57BL6Fbxl5GtOST386421LexFbxl5Fbxl5Fbxl5GtOST386421Lex