Zhengxin. Jiang, et.al., Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development., Human molecular genetics, 2013, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23184148

Zhengxin. Jiang, et.al., Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development., Human molecular genetics, 2013, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Zic3<tm2.1Jwb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5470150

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hindlimb paralysis_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000755I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• situs inversus_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0002766I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal embryo development_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001672I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• situs inversus_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0002766I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• ventricular septal defect_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0010402I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal head morphology_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0000432I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• abnormal stomach position or orientation_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0010807I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• ventricular septal defect_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0010402I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• heterotaxia_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004133I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• preweaning lethality, incomplete penetrance_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0011110I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• abnormal eye morphology_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002092I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal heart position or orientation_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0006065I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• embryonic growth retardation_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0003984I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• cleft palate_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0000111I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• open neural tube_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0000929I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• kinked tail_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000585I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• atrial septal defect_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0010403I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• double outlet right ventricle_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0000284I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal heart position or orientation_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0006065I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• atrial septal defect_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0010403I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• preweaning lethality, incomplete penetrance_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0011110I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• no abnormal phenotype detected_Zic3<tm2.1Jwb>/Zic3<tm2.1Jwb>
  http://metadb.riken.jp/0002169I129S4SvJaeSor129S7SvSvBrdC57BL6JZic3tm21JwbZic3tm21JwbZic3tm21Jwb
• abnormal axial skeleton morphology_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002114I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• heterotaxia_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0004133I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• no abnormal phenotype detected_Zic3<tm2.1Jwb>/Y
  http://metadb.riken.jp/0002169I129S4SvJaeSor129S7SvSvBrdC57BL6JZic3tm21JwbYZic3tm21Jwb
• embryonic growth retardation_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0003984I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• lethality throughout fetal growth and development, incomplete penetrance_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011109I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• right-sided stomach_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0010808I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• exencephaly_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0000914I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• cleft palate_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0000111I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• abnormal direction of heart looping_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004252I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal lung position or orientation_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0010853I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• dextrocardia_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0000644I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal direction of heart looping_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0004252I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• abnormal heart looping_Zic3<tm2.1Jwb>/Y,Tg(T-cre)1Lwd/0
  http://metadb.riken.jp/0000269I129S4SvJaeSor129S7SvSvBrdC3HC57BL6Zic3tm21JwbYTgTcre1Lwd0TgTcre1LwdZic3tm21Jwb
• abnormal neural tube morphology_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002151I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• dextrocardia_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0000644I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• lung situs inversus_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0010854I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• preweaning lethality, incomplete penetrance_Zic3<tm2.1Jwb>/Y,Tg(T-cre)1Lwd/0
  http://metadb.riken.jp/0011110I129S4SvJaeSor129S7SvSvBrdC3HC57BL6Zic3tm21JwbYTgTcre1Lwd0TgTcre1LwdZic3tm21Jwb
• right-sided stomach_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0010808I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• cleft palate_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000111I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• no abnormal phenotype detected_Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>,Zic3<tm2.1Jwb>/Y
  http://metadb.riken.jp/0002169I129S4SvJaeSor129S7SvSvBrdC57BL6JNkx25tm1creRjsNkx25Zic3tm21JwbYZic3tm21JwbNkx25tm1creRjsNkx25
• right aortic arch_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0004158I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal inferior vena cava morphology_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0006063I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• heterotaxia_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0004133I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• exencephaly_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0000914I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal inferior vena cava morphology_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0006063I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal head morphology_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0000432I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal inferior vena cava morphology_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0006063I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• dextrocardia_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000644I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• no abnormal phenotype detected_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Zic3<tm2.1Jwb>/Y
  http://metadb.riken.jp/0002169I129S4SvJaeSor129S7SvSvBrdC57BL6CBAJNCrljMesp1tm2creYsaMesp1Zic3tm21JwbYZic3tm21JwbMesp1tm2creYsaMesp1
• abnormal heart looping_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0000269I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• abnormal neural tube morphology_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0002151I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• abnormal stomach position or orientation_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0010807I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• kinked tail_Zic3<tm2.1Jwb>/Y,Tg(T-cre)1Lwd/0
  http://metadb.riken.jp/0000585I129S4SvJaeSor129S7SvSvBrdC3HC57BL6Zic3tm21JwbYTgTcre1Lwd0TgTcre1LwdZic3tm21Jwb
• heterotaxia_Zic3<tm2.1Jwb>/Y,Tg(T-cre)1Lwd/0
  http://metadb.riken.jp/0004133I129S4SvJaeSor129S7SvSvBrdC3HC57BL6Zic3tm21JwbYTgTcre1Lwd0TgTcre1LwdZic3tm21Jwb
• abnormal stomach position or orientation_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0010807I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• no abnormal phenotype detected_Zic3<tm2.1Jwb>/Y,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002169I129S4SvJaeSor129S7SvSvBrdC57BL6JCBAJZic3tm21JwbYTgWnt1cre11Rth0Zic3tm21JwbTgWnt1cre11Rth
• abnormal lung position or orientation_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0010853I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• embryonic growth retardation_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003984I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal heart looping_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0000269I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca
• right-sided stomach_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0010808I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• abnormal neural tube morphology_Zic3<tm1Bca>/Zic3<tm1Bca>
  http://metadb.riken.jp/0002151I129S7SvEvBrdZic3tm1BcaZic3tm1BcaZic3tm1Bca
• exencephaly_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000914I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal anus morphology_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0005034I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal heart looping_Zic3<tm2.1Jwb>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000269I129S4SvJaeSor129S7SvSvBrdC57BL6CBAZic3tm21JwbYTgSox2cre1Amc0Zic3tm21JwbTgSox2cre1Amc
• abnormal direction of heart looping_Zic3<tm1Bca>/Y
  http://metadb.riken.jp/0004252I129S7SvEvBrdZic3tm1BcaYZic3tm1Bca

class

http://purl.org/net/cito/citesAsAuthority

• Zic3<tm2.1Jwb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5470150