Ruan. Zhang, et.al., An obligate cell-intrinsic function for CD28 in Tregs., The Journal of clinical investigation, 2013, 123

http://rdf.ncbi.nlm.nih.gov/pubmed/23281398

Ruan. Zhang, et.al., An obligate cell-intrinsic function for CD28 in Tregs., The Journal of clinical investigation, 2013, 123

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cd28<tm1Ltu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5485211

class

http://purl.org/net/cito/citesAsAuthority

• Cd28<tm1Ltu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5485211

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• focal hair loss_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0000418I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• ruffled hair_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0000420I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• enlarged spleen_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• enlarged lymph nodes_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0000702I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• skin lesions_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0001212I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• abnormal eyelid morphology_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0001340I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
他9件を見る
• hypoactivity_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0001402I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• hunched posture_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0001505I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• increased activated T cell number_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0001829I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• increased susceptibility to experimental autoimmune encephalomyelitis_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0004799I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• skin inflammation_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0004947I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• decreased regulatory T cell number_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0004974I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• increased B cell number_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0005014I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• decreased T cell proliferation_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0005095I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr
• increased susceptibility to autoimmune disorder_Cd28<tm1Ltu>/Cd28<tm1Ltu>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>
  http://metadb.riken.jp/0005350I129S1Sv129X1SvJC57BL6Cd28tm1LtuCd28tm1LtuFoxp3tm4YFPicreAyrFoxp3Foxp3Cd28tm1LtuFoxp3tm4YFPicreAyr