Fiona. McMurray, et.al., Adult onset global loss of the fto gene alters body composition and metabolism in the mouse., PLoS genetics, 2013, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/23300482

Fiona. McMurray, et.al., Adult onset global loss of the fto gene alters body composition and metabolism in the mouse., PLoS genetics, 2013, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fto<tm1.2Rdc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5494490
• Fto<tm1.1Rdc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5494489

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• preweaning lethality, incomplete penetrance_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0011110I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• decreased food intake_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>
  http://metadb.riken.jp/0011940I129S1Sv129X1SvJC57BL6Ftotm11RdcFtotm11RdcFtotm11Rdc
• premature death_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0002083I129SSvEv129S1Sv129X1SvJC57BL6SJLFtotm11RdcFtotm11RdcTgUBCcreERT21Ejb0Ftotm11RdcTgUBCcreERT21Ejb
• decreased respiratory quotient_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0010379I129SSvEv129S1Sv129X1SvJC57BL6SJLFtotm11RdcFtotm11RdcTgUBCcreERT21Ejb0Ftotm11RdcTgUBCcreERT21Ejb
• decreased body weight_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6Ftotm11RdcFtotm11RdcFtotm11Rdc
• decreased lean body mass_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0003961I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• improved glucose tolerance_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0005292I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• decreased respiratory quotient_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0010379I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• increased food intake_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0011939I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• decreased lean body mass_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0003961I129SSvEv129S1Sv129X1SvJC57BL6SJLFtotm11RdcFtotm11RdcTgUBCcreERT21Ejb0Ftotm11RdcTgUBCcreERT21Ejb
• increased oxygen consumption_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0005289I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• decreased carbon dioxide production_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0008964I129SSvEv129S1Sv129X1SvJC57BL6SJLFtotm11RdcFtotm11RdcTgUBCcreERT21Ejb0Ftotm11RdcTgUBCcreERT21Ejb
• decreased body weight_Fto<tm1.2Rdc>/Fto<tm1.2Rdc>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6C57BL6JSJLFtotm12RdcFtotm12RdcFtotm12Rdc
• decreased body weight_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0001262I129SSvEv129S1Sv129X1SvJC57BL6SJLFtotm11RdcFtotm11RdcTgUBCcreERT21Ejb0Ftotm11RdcTgUBCcreERT21Ejb
• increased total body fat amount_Fto<tm1.1Rdc>/Fto<tm1.1Rdc>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0010024I129SSvEv129S1Sv129X1SvJC57BL6SJLFtotm11RdcFtotm11RdcTgUBCcreERT21Ejb0Ftotm11RdcTgUBCcreERT21Ejb

class

http://purl.org/net/cito/citesAsAuthority

• Fto<tm1.2Rdc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5494490
• Fto<tm1.1Rdc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5494489