Sutada. Lotinun, et.al., Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation., The Journal of clinical investigation, 2013, 123

http://rdf.ncbi.nlm.nih.gov/pubmed/23321671

Sutada. Lotinun, et.al., Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation., The Journal of clinical investigation, 2013, 123

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctsk<tm1.1Rbar>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5492037

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal osteoblast differentiation_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008395IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased bone volume_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0010875IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased trabecular bone mass_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0010872IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• abnormal osteoclast differentiation_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008396IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased osteoclast cell number_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0004984IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased trabecular bone thickness_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0009347IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased compact bone volume_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0010964IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased bone mineralization_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0020080IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased bone ossification_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0020039IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased osteoblast cell number_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004988IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased bone trabecula number_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010868IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• abnormal osteoclast physiology_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001541IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased osteoblast cell number_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0004988IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• abnormal osteoblast physiology_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005006IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased trabecular bone volume_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,X/Tg(Itgam-cre)AJva
  http://metadb.riken.jp/0010878IC57BL6Ctsktm11RbarCtsktm11RbarXTgItgamcreAJvaTgItgamcreAJvaCtsktm11Rbar
• increased trabecular bone mass_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010872IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased osteoclast cell number_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004984IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased trabecular bone connectivity density_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010932IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar
• increased trabecular bone volume_Ctsk<tm1.1Rbar>/Ctsk<tm1.1Rbar>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010878IC57BL6CBACtsktm11RbarCtsktm11RbarTgMx1cre1Cgn0TgMx1cre1CgnCtsktm11Rbar

class

http://purl.org/net/cito/citesAsAuthority

• Ctsk<tm1.1Rbar>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5492037