Samuel M. Lee, et.al., Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C., Human molecular genetics, 2013, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23359569

Samuel M. Lee, et.al., Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C., Human molecular genetics, 2013, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/db/mgi_rdf/MGI:5478742

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/db/mgi_rdf/MGI:5478742

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myelin sheath morphology_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0003871FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• hyporesponsive to tactile stimuli_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0005498FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• abnormal node of Ranvier morphology_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0010732FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• axon degeneration_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0005405FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• abnormal behavior_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0004924FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• abnormal sciatic nerve morphology_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0002651FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• decreased nerve conduction velocity_Tg(CMV-LITAF*W116G)#Lli/0
  http://metadb.riken.jp/0008814FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLli0TgCMVLITAFW116GLli
• abnormal paranode morphology_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0010734FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• abnormal myelination_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0000920FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• demyelination_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0000921FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• abnormal juxtaparanode morphology_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0010737FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• impaired coordination_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0001405FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• decreased nerve conduction velocity_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0008814FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• impaired coordination_Tg(CMV-LITAF*W116G)#Lli/0
  http://metadb.riken.jp/0001405FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLli0TgCMVLITAFW116GLli
• abnormal action potential_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0005402FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• limb grasping_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0001513FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli
• abnormal axon morphology_Tg(CMV-LITAF*W116G)#Lli/Tg(CMV-LITAF*W116G)#Lli
  http://metadb.riken.jp/0005404FVBTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLliTgCMVLITAFW116GLli