Fatemehsadat. Esteghamat, et.al., Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice., Blood, 2013, 121

http://rdf.ncbi.nlm.nih.gov/pubmed/23361909

Fatemehsadat. Esteghamat, et.al., Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice., Blood, 2013, 121

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bcl11a<tm1Mbu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5496827
• Tg(HBB)8.1Gvs
  http://metadb.riken.jp/db/mgi_rdf/MGI:5496829

class

http://purl.org/net/cito/citesAsAuthority

• Bcl11a<tm1Mbu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5496827
• Tg(HBB)8.1Gvs
  http://metadb.riken.jp/db/mgi_rdf/MGI:5496829

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating erythropoietin level_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0011285I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• reticulocytosis_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002640I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• polychromatophilia_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0005097I129P2OlaHsdBALBcJFVBNBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1Eportm1EGFPcreUkEporTgHBB81Gvs0Klf1tm1NimrTgHBB81GvsBcl11atm1MbuEporEportm1EGFPcreUkKlf1
• decreased hematocrit_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0000208I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu
• decreased erythrocyte cell number_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002875I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• reticulocytosis_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002640I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu
• decreased mean corpuscular volume_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002591I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• polychromatophilia_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0005097I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• abnormal erythropoiesis_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0000245I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• increased circulating erythropoietin level_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0011285I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu
• decreased hematocrit_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0000208I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• abnormal erythropoiesis_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0000245I129P2OlaHsdBALBcJFVBNBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1Eportm1EGFPcreUkEporTgHBB81Gvs0Klf1tm1NimrTgHBB81GvsBcl11atm1MbuEporEportm1EGFPcreUkKlf1
• anemia_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0001577I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• decreased hemoglobin content_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002874I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• anemia_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0001577I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu
• abnormal erythropoiesis_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0000245I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu
• decreased hemoglobin content_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002874I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu
• decreased mean corpuscular hemoglobin_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Klf1<tm1Nimr>/Klf1<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0005562I129P2OlaHsdFVBBcl11atm1MbuBcl11atm1MbuKlf1tm1NimrKlf1TgHBB81Gvs0Klf1tm1NimrBcl11atm1MbuTgHBB81GvsKlf1
• decreased erythrocyte cell number_Bcl11a<tm1Mbu>/Bcl11a<tm1Mbu>,Epor<tm1(EGFP/cre)Uk>/Epor<+>,Tg(HBB)8.1Gvs/0
  http://metadb.riken.jp/0002875I129BALBcJFVBNBcl11atm1MbuBcl11atm1MbuEportm1EGFPcreUkEporTgHBB81Gvs0Eportm1EGFPcreUkTgHBB81GvsEporBcl11atm1Mbu