Ines. Taes, et.al., Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS., Human molecular genetics, 2013, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23364049

Ines. Taes, et.al., Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS., Human molecular genetics, 2013, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sirt2<tm1.2Auw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5499209

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal action potential_Sirt2<tm1.2Auw>/Sirt2<tm1.2Auw>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0005402I129C57BL6C57BL6JSJLSirt2tm12AuwSirt2tm12AuwTgSOD1G93A1Gur0Sirt2tm12AuwTgSOD1G93A1Gur
• increased neuron number_Hdac6<tm1.1Pmt>/Y,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0008947I129P2OlaHsdC57BL6C57BL6JSJLHdac6tm11PmtYTgSOD1G93A1Gur0TgSOD1G93A1GurHdac6tm11Pmt
• premature death_Sirt2<tm1.2Auw>/Sirt2<tm1.2Auw>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0002083I129C57BL6C57BL6JSJLSirt2tm12AuwSirt2tm12AuwTgSOD1G93A1Gur0Sirt2tm12AuwTgSOD1G93A1Gur
• abnormal innervation pattern to muscle_Sirt2<tm1.2Auw>/Sirt2<tm1.2Auw>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0001052I129C57BL6C57BL6JSJLSirt2tm12AuwSirt2tm12AuwTgSOD1G93A1Gur0Sirt2tm12AuwTgSOD1G93A1Gur
• abnormal survival_Hdac6<tm1.1Pmt>/Y,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0010769I129P2OlaHsdC57BL6C57BL6JSJLHdac6tm11PmtYTgSOD1G93A1Gur0TgSOD1G93A1GurHdac6tm11Pmt
• decreased neuron number_Sirt2<tm1.2Auw>/Sirt2<tm1.2Auw>,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0008948I129C57BL6C57BL6JSJLSirt2tm12AuwSirt2tm12AuwTgSOD1G93A1Gur0Sirt2tm12AuwTgSOD1G93A1Gur
• decreased grip strength_Hdac6<tm1.1Pmt>/Y,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0010053I129P2OlaHsdC57BL6C57BL6JSJLHdac6tm11PmtYTgSOD1G93A1Gur0TgSOD1G93A1GurHdac6tm11Pmt
• abnormal innervation pattern to muscle_Hdac6<tm1.1Pmt>/Y,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0001052I129P2OlaHsdC57BL6C57BL6JSJLHdac6tm11PmtYTgSOD1G93A1Gur0TgSOD1G93A1GurHdac6tm11Pmt
• abnormal action potential_Hdac6<tm1.1Pmt>/Y,Tg(SOD1*G93A)1Gur/0
  http://metadb.riken.jp/0005402I129P2OlaHsdC57BL6C57BL6JSJLHdac6tm11PmtYTgSOD1G93A1Gur0TgSOD1G93A1GurHdac6tm11Pmt

class

http://purl.org/net/cito/citesAsAuthority

• Sirt2<tm1.2Auw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5499209