Maria. Di Bonito, et.al., Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem., PLoS genetics, 2013, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/23408898

Maria. Di Bonito, et.al., Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem., PLoS genetics, 2013, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Hoxb1-cre)r4Mist
  http://metadb.riken.jp/db/mgi_rdf/MGI:5006714
• Hoxb1<tm1Mist>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5287653
• Hoxb1<tm1.1Mist>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5287678
• Hoxb2<tm3.1Fmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5490993
• Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5490994

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Hoxb1-cre)r4Mist
  http://metadb.riken.jp/db/mgi_rdf/MGI:5006714
• Hoxb1<tm1Mist>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5287653
• Hoxb1<tm1.1Mist>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5287678
• Hoxb2<tm3.1Fmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5490993
• Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5490994

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal organ of Corti morphology_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000042I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• abnormal organ of Corti morphology_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000042I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• abnormal organ of Corti morphology_Hoxb2<tm3.2Fmr>/Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/0000042I129S2SvPasC57BL6Hoxb2tm32FmrHoxb2tm32FmrHoxb2tm32Fmr
• abnormal pons morphology_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000848I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• abnormal pons morphology_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000848I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• abnormal pons morphology_Hoxb2<tm3.2Fmr>/Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/0000848I129S2SvPasC57BL6Hoxb2tm32FmrHoxb2tm32FmrHoxb2tm32Fmr
他19件を見る
• no abnormal phenotype detected_Hoxb2<tm3.1Fmr>/Hoxb2<+>
  http://metadb.riken.jp/0002169I129S2SvPasC57BL6Hoxb2tm31FmrHoxb2Hoxb2Hoxb2tm31Fmr
• no abnormal phenotype detected_Hoxb2<tm3.1Fmr>/Hoxb2<tm3.1Fmr>
  http://metadb.riken.jp/0002169I129S2SvPasC57BL6Hoxb2tm31FmrHoxb2tm31FmrHoxb2tm31Fmr
• abnormal cochlear outer hair cell morphology_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004399I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• abnormal cochlear outer hair cell morphology_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004399I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• abnormal cochlear outer hair cell morphology_Hoxb2<tm3.2Fmr>/Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/0004399I129S2SvPasC57BL6Hoxb2tm32FmrHoxb2tm32FmrHoxb2tm32Fmr
• increased susceptibility to age-related hearing loss_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004748I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• increased susceptibility to age-related hearing loss_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004748I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• abnormal brainstem morphology_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005277I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• abnormal brainstem morphology_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005277I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• abnormal brainstem morphology_Hoxb2<tm3.2Fmr>/Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/0005277I129S2SvPasC57BL6Hoxb2tm32FmrHoxb2tm32FmrHoxb2tm32Fmr
• lethality throughout fetal growth and development_Hoxa2<tm1.1Fmr>/Hoxa2<tm1.1Fmr>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0006208I129S2SvPasC57BL6SJLHoxa2tm11FmrHoxa2tm11FmrTgWnt1cre11Rth0Hoxa2tm11FmrTgWnt1cre11Rth
• abnormal susceptibility to hearing loss_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0006334I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• increased or absent threshold for auditory brainstem response_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0011967I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• increased or absent threshold for auditory brainstem response_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0011967I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• increased or absent threshold for auditory brainstem response_Hoxb2<tm3.2Fmr>/Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/0011967I129S2SvPasC57BL6Hoxb2tm32FmrHoxb2tm32FmrHoxb2tm32Fmr
• abnormal cochlear VIII nucleus morphology_Hoxb1<tm1.1Mist>/Hoxb1<tm1.1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0012490I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm11MistHoxb1tm11MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorGtROSA26Sortm1EYFPCosHoxb1tm11MistGtROSA26SorTgHoxb1crer4Mist
• abnormal cochlear VIII nucleus morphology_Hoxb1<tm1Mist>/Hoxb1<tm1Mist>,Tg(Hoxb1-cre)r4Mist/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0012490I129S2SvPas129X1SvJC57BL6CD1Hoxb1tm1MistHoxb1tm1MistTgHoxb1crer4Mist0GtROSA26Sortm1EYFPCosGtROSA26SorHoxb1tm1MistGtROSA26Sortm1EYFPCosTgHoxb1crer4MistGtROSA26Sor
• abnormal cochlear VIII nucleus morphology_Hoxb2<tm3.2Fmr>/Hoxb2<tm3.2Fmr>
  http://metadb.riken.jp/0012490I129S2SvPasC57BL6Hoxb2tm32FmrHoxb2tm32FmrHoxb2tm32Fmr
• abnormal cochlear VIII nucleus morphology_Hoxa2<tm1.1Fmr>/Hoxa2<tm1.1Fmr>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0012490I129S2SvPasC57BL6SJLHoxa2tm11FmrHoxa2tm11FmrTgWnt1cre11Rth0Hoxa2tm11FmrTgWnt1cre11Rth