Andreas. Billich, et.al., Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis., PloS one, 2013, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/23544080

Andreas. Billich, et.al., Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis., PloS one, 2013, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514381
• Sgpl1<tm1.2Npa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514382
• Actb<tm4(cre/ERT2)Npa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514361

class

http://purl.org/net/cito/citesAsAuthority

• Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514381
• Sgpl1<tm1.2Npa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514382
• Actb<tm4(cre/ERT2)Npa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514361

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased marginal zone B cell number_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0008182IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• abnormal lipid homeostasis_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0002118IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• decreased susceptibility to experimental autoimmune encephalomyelitis_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0004800IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• increased thymocyte number_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0000714IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• abnormal regulatory T cell number_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0004972IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• decreased follicular B cell number_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0008174IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• spleen hypoplasia_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0000694IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• abnormal postnatal growth_Sgpl1<tm1.2Npa>/Sgpl1<tm1.2Npa>
  http://metadb.riken.jp/0001731IBALBcJC57BL6Sgpl1tm12NpaSgpl1tm12NpaSgpl1tm12Npa
• spleen hypoplasia_Sgpl1<tm1.2Npa>/Sgpl1<tm1.2Npa>
  http://metadb.riken.jp/0000694IBALBcJC57BL6Sgpl1tm12NpaSgpl1tm12NpaSgpl1tm12Npa
• postnatal lethality_Sgpl1<tm1.2Npa>/Sgpl1<tm1.2Npa>
  http://metadb.riken.jp/0002082IBALBcJC57BL6Sgpl1tm12NpaSgpl1tm12NpaSgpl1tm12Npa
• abnormal lipid homeostasis_Sgpl1<tm1.2Npa>/Sgpl1<tm1.2Npa>
  http://metadb.riken.jp/0002118IBALBcJC57BL6Sgpl1tm12NpaSgpl1tm12NpaSgpl1tm12Npa
• abnormal type IV hypersensitivity reaction_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0002534IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• abnormal lymph node morphology_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0002339IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa
• decreased single-positive T cell number_Actb<tm4(cre/ERT2)Npa>/Actb<+>,Sgpl1<tm1.1Npa>/Sgpl1<tm1.1Npa>
  http://metadb.riken.jp/0008083IBALBcJC57BL6Actbtm4creERT2NpaActbSgpl1tm11NpaSgpl1tm11NpaActbtm4creERT2NpaActbSgpl1tm11Npa