Pascal. Seyer, et.al., Hepatic glucose sensing is required to preserve β cell glucose competence., The Journal of clinical investigation, 2013, 123

http://rdf.ncbi.nlm.nih.gov/pubmed/23549084

Pascal. Seyer, et.al., Hepatic glucose sensing is required to preserve β cell glucose competence., The Journal of clinical investigation, 2013, 123

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Slc2a2<tm2Thor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514187

class

http://purl.org/net/cito/citesAsAuthority

• Slc2a2<tm2Thor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5514187

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased muscle cell glucose uptake_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0030021I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• abnormal bile salt level_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0004774I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• decreased insulin secretion_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0003059I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• abnormal glycogen homeostasis_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0005438I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• increased liver glycogen level_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0010400I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• impaired glucose tolerance_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0005293I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• abnormal glucose homeostasis_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0002078I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• abnormal circulating glucose level_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0000188I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• decreased liver cholesterol level_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0010026I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• abnormal lipid homeostasis_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0002118I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• decreased liver triglyceride level_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0009356I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor
• impaired cellular glucose import_Alb<tm1(cre/ERT2)Mtz>/Alb<tm1(cre/ERT2)Mtz>,Slc2a2<tm2Thor>/Slc2a2<tm2Thor>
  http://metadb.riken.jp/0003926I129P2OlaHsd129S2SvPasC57BL6Albtm1creERT2MtzAlbtm1creERT2MtzSlc2a2tm2ThorSlc2a2tm2ThorAlbtm1creERT2MtzSlc2a2tm2Thor