Alvin. Pratama, et.al., Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation., Immunity, 2013, 38

http://rdf.ncbi.nlm.nih.gov/pubmed/23583642

Alvin. Pratama, et.al., Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation., Immunity, 2013, 38

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rc3h1<tm1.1Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508920
• Rc3h1<tm1.2Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508923
• Rc3h2<tm1.1Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508926
• Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508928

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor necrosis factor secretion_Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0008560IC57BL6Rc3h2tm12CgvRc3h2tm12CgvRc3h2tm12Cgv
• abnormal lung development_Rc3h1<tm1.2Cgv>/Rc3h1<tm1.2Cgv>
  http://metadb.riken.jp/0001176IC57BL6Rc3h1tm12CgvRc3h1tm12CgvRc3h1tm12Cgv
• increased inflammatory response_Rc3h1<san>/Rc3h1<san>,Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0001846IC57BL6C57BL6JSfdAnuRc3h1sanRc3h1sanRc3h2tm12CgvRc3h2tm12CgvRc3h1sanRc3h2tm12Cgv
• perinatal lethality, complete penetrance_Rc3h1<tm1.2Cgv>/Rc3h1<tm1.2Cgv>
  http://metadb.riken.jp/0011089IC57BL6Rc3h1tm12CgvRc3h1tm12CgvRc3h1tm12Cgv
• increased macrophage cytokine production_Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0011078IC57BL6Rc3h2tm12CgvRc3h2tm12CgvRc3h2tm12Cgv
• increased T follicular helper cell number_Rc3h1<tm1.2Cgv>/Rc3h1<san>
  http://metadb.riken.jp/0010186IC57BL6C57BL6JSfdAnuRc3h1tm12CgvRc3h1sanRc3h1sanRc3h1tm12Cgv
• increased T follicular helper cell number_Rc3h1<san>/Rc3h1<san>,Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0010186IC57BL6C57BL6JSfdAnuRc3h1sanRc3h1sanRc3h2tm12CgvRc3h2tm12CgvRc3h1sanRc3h2tm12Cgv
• premature death_Rc3h1<san>/Rc3h1<san>,Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0002083IC57BL6C57BL6JSfdAnuRc3h1sanRc3h1sanRc3h2tm12CgvRc3h2tm12CgvRc3h1sanRc3h2tm12Cgv
• increased circulating tumor necrosis factor level_Rc3h1<san>/Rc3h1<san>
  http://metadb.riken.jp/0008553IC57BL6JSfdAnuRc3h1sanRc3h1sanRc3h1san
• kidney inflammation_Rc3h1<san>/Rc3h1<san>,Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0001859IC57BL6C57BL6JSfdAnuRc3h1sanRc3h1sanRc3h2tm12CgvRc3h2tm12CgvRc3h1sanRc3h2tm12Cgv
• abnormal neural tube closure_Rc3h1<tm1.2Cgv>/Rc3h1<tm1.2Cgv>
  http://metadb.riken.jp/0003720IC57BL6Rc3h1tm12CgvRc3h1tm12CgvRc3h1tm12Cgv
• increased circulating tumor necrosis factor level_Rc3h1<san>/Rc3h1<san>,Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0008553IC57BL6C57BL6JSfdAnuRc3h1sanRc3h1sanRc3h2tm12CgvRc3h2tm12CgvRc3h1sanRc3h2tm12Cgv
• increased CD4-positive, alpha beta T cell number_Rc3h1<tm1.2Cgv>/Rc3h1<san>
  http://metadb.riken.jp/0008074IC57BL6C57BL6JSfdAnuRc3h1tm12CgvRc3h1sanRc3h1sanRc3h1tm12Cgv
• increased susceptibility to bacterial infection_Rc3h1<san>/Rc3h1<san>,Rc3h2<tm1.2Cgv>/Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/0002412IC57BL6C57BL6JSfdAnuRc3h1sanRc3h1sanRc3h2tm12CgvRc3h2tm12CgvRc3h1sanRc3h2tm12Cgv

class

http://purl.org/net/cito/citesAsAuthority

• Rc3h1<tm1.1Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508920
• Rc3h1<tm1.2Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508923
• Rc3h2<tm1.1Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508926
• Rc3h2<tm1.2Cgv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508928