Weiqiang. Lin, et.al., Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity., The EMBO journal, 2013, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/23604072

Weiqiang. Lin, et.al., Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity., The EMBO journal, 2013, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dna2<tm1.1Lzhg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515895

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality, complete penetrance_Dna2<tm1.1Lzhg>/Dna2<tm1.1Lzhg>
  http://metadb.riken.jp/0011092I129S1SvDna2tm11LzhgDna2tm11LzhgDna2tm11Lzhg
• increased lymphoma incidence_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0012431I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• chromosomal instability_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0008866I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• abnormal mitosis_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0004046I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• abnormal chromosome morphology_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0003702I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• abnormal telomere morphology_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0010207I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• increased lung adenocarcinoma incidence_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0002027I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• increased hepatoma incidence_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0010264I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• abnormal telomere length_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0003155I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg
• aneuploidy_Dna2<tm1.1Lzhg>/Dna2<+>
  http://metadb.riken.jp/0004024I129S1SvDna2tm11LzhgDna2Dna2Dna2tm11Lzhg

class

http://purl.org/net/cito/citesAsAuthority

• Dna2<tm1.1Lzhg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515895