Claire E. Kelly, et.al., Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension., PLoS biology, 2013, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/23610558

Claire E. Kelly, et.al., Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension., PLoS biology, 2013, 11

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rnf165<Gt(P9-3F)Sor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5516581

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal motor neuron innervation pattern_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000940I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• skeletal muscle atrophy_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0009417I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• abnormal axon extension_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0003651I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal joint mobility_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0008069I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• prenatal lethality, incomplete penetrance_Bmpr2<tm1Kmi>/Bmpr2<+>,Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0011101I129S4SvJaeC57BL6CBABmpr2tm1KmiBmpr2Rnf165GtP93FSorRnf165TgHlxb9GFP1Tmj0Rnf165GtP93FSorBmpr2tm1KmiTgHlxb9GFP1TmjBmpr2Rnf165
• hypoxia_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0005039I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• skeletal muscle atrophy_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0009417I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• neonatal lethality, incomplete penetrance_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0011088I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• prenatal lethality, incomplete penetrance_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0011101I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• abnormal phrenic nerve innervation pattern to diaphragm_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0012055I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal body size_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0003956I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• cyanosis_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0001575I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• postnatal growth retardation_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0001732I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal autopod morphology_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000572I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal motor neuron innervation pattern_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000940I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal hindlimb morphology_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000556I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• decreased grip strength_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0010053I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal forelimb morphology_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000550I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• abnormal forelimb morphology_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000550I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• increased circulating lactate level_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0013405I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• decreased grip strength_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0010053I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• aphagia_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0001438I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• postnatal lethality, complete penetrance_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0011085I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• postnatal lethality, incomplete penetrance_Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Smad9<tm1Rob>/Smad9<tm1Rob>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0011086I129SSvEvC57BL6CBARnf165GtP93FSorRnf165Smad9tm1RobSmad9tm1RobTgHlxb9GFP1Tmj0Rnf165Rnf165GtP93FSorSmad9tm1RobTgHlxb9GFP1Tmj
• abnormal motor neuron innervation pattern_Bmpr2<tm1Kmi>/Bmpr2<+>,Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0000940I129S4SvJaeC57BL6CBABmpr2tm1KmiBmpr2Rnf165GtP93FSorRnf165TgHlxb9GFP1Tmj0Rnf165GtP93FSorBmpr2tm1KmiTgHlxb9GFP1TmjBmpr2Rnf165
• dehydration_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0001429I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• decreased body size_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0001265I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• abnormal joint mobility_Rnf165<Gt(P9-3F)Sor>/Rnf165<Gt(P9-3F)Sor>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0008069I129S4SvJaeSorC57BL6CBARnf165GtP93FSorRnf165GtP93FSorTgHlxb9GFP1Tmj0Rnf165GtP93FSorTgHlxb9GFP1Tmj
• decreased grip strength_Bmpr2<tm1Kmi>/Bmpr2<+>,Rnf165<Gt(P9-3F)Sor>/Rnf165<+>,Tg(Hlxb9-GFP)1Tmj/0
  http://metadb.riken.jp/0010053I129S4SvJaeC57BL6CBABmpr2tm1KmiBmpr2Rnf165GtP93FSorRnf165TgHlxb9GFP1Tmj0Rnf165GtP93FSorBmpr2tm1KmiTgHlxb9GFP1TmjBmpr2Rnf165

class

http://purl.org/net/cito/citesAsAuthority

• Rnf165<Gt(P9-3F)Sor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5516581