Xidao. Wang, et.al., Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch., Neuron, 2013, 78

http://rdf.ncbi.nlm.nih.gov/pubmed/23622066

Xidao. Wang, et.al., Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch., Neuron, 2013, 78

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nr2c2<tm1Bbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5517362

class

http://purl.org/net/cito/citesAsAuthority

• Nr2c2<tm1Bbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5517362

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron physiology_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004811IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• decreased body size_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001265IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• decreased neuron number_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008948IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• decreased anxiety-related response_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001364IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• impaired coordination_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001405IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• increased chemical nociceptive threshold_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0008531NSNr2c2tm1BbmNr2c2tm1BbmPax3tm1creJoePax3Nr2c2tm1BbmPax3Pax3tm1creJoe
• abnormal touch/ nociception_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001968IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• abnormal mechanical nociception_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002734IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• abnormal mechanical nociception_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0002734NSNr2c2tm1BbmNr2c2tm1BbmPax3tm1creJoePax3Nr2c2tm1BbmPax3Pax3tm1creJoe
• increased thermal nociceptive threshold_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0001973NSNr2c2tm1BbmNr2c2tm1BbmPax3tm1creJoePax3Nr2c2tm1BbmPax3Pax3tm1creJoe
• decreased pruritus_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0010073IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• decreased neuron number_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0008948NSNr2c2tm1BbmNr2c2tm1BbmPax3tm1creJoePax3Nr2c2tm1BbmPax3Pax3tm1creJoe
• decreased pruritus_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0010073NSNr2c2tm1BbmNr2c2tm1BbmPax3tm1creJoePax3Nr2c2tm1BbmPax3Pax3tm1creJoe
• increased chemical nociceptive threshold_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008531IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• increased thermal nociceptive threshold_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001973IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm
• abnormal sympathetic afferent fiber morphology_Nr2c2<tm1Bbm>/Nr2c2<tm1Bbm>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008319IC57BL6SJLNr2c2tm1BbmNr2c2tm1BbmTgNescre1Kln0TgNescre1KlnNr2c2tm1Bbm