Javier A. Tello, et.al., Reproductive physiology of a humanized GnRH receptor mouse model: application in evaluation of human-specific analogs., American journal of physiology. Endocrinology and metabolism, 2013, 305

http://rdf.ncbi.nlm.nih.gov/pubmed/23632635

Javier A. Tello, et.al., Reproductive physiology of a humanized GnRH receptor mouse model: application in evaluation of human-specific analogs., American journal of physiology. Endocrinology and metabolism, 2013, 305

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5517591

class

http://purl.org/net/cito/citesAsAuthority

• Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5517591

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating testosterone level_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0002780IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• abnormal response to injury_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0005164IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• reduced female fertility_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0001923IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• increased circulating estradiol level_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0005182IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• prolonged metestrus_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0009020IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• decreased circulating luteinizing hormone level_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0002773IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• prolonged estrous cycle_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0009006IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• abnormal estrous cycle_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0001927IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen
• abnormal luteinizing hormone level_Gnrhr<tm1(GNRHR1)Xen>/Gnrhr<tm1(GNRHR1)Xen>
  http://metadb.riken.jp/0003969IC57BL6C57BL6JOlaHsdGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1XenGnrhrtm1GNRHR1Xen