Maria L. Allende, et.al., Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis., The Journal of biological chemistry, 2013, 288

http://rdf.ncbi.nlm.nih.gov/pubmed/23637227

Maria L. Allende, et.al., Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis., The Journal of biological chemistry, 2013, 288

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal ceramide level_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0012232IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• thick epidermis_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0001219IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• abnormal keratinocyte differentiation_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002656IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• abnormal skin appearance_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0009931IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• increased keratinocyte proliferation_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0009583IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• abnormal epidermal layer morphology_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0001216IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• impaired skin barrier function_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002796IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• abnormal epidermis stratum corneum morphology_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0001240IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• thick epidermis stratum basale_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0009715IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• abnormal skin physiology_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0005501IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• decreased body size_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0001265IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• postnatal lethality, incomplete penetrance_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0011086IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• thick epidermis stratum spinosum_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0009474IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg
• thick epidermis stratum granulosum_Sgpp1<tm1(KOMP)Vlcg>/Sgpp1<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0009599IC57BL6NTacSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcgSgpp1tm1KOMPVlcg