Qiulin. Tan, et.al., Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation., The Journal of biological chemistry, 2013, 288

http://rdf.ncbi.nlm.nih.gov/pubmed/23640890

Qiulin. Tan, et.al., Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation., The Journal of biological chemistry, 2013, 288

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Epas1<tm1.1Fsl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5518445

class

http://purl.org/net/cito/citesAsAuthority

• Epas1<tm1.1Fsl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5518445

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased hematocrit_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0002608IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased hemoglobin content_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0005564IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased hematocrit_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0002608IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• increased leukocyte cell number_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0000218IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased monocyte cell number_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0000220IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• lethality, incomplete penetrance_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0010831IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• abnormal heart right ventricle pressure_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0010755IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• increased pulmonary respiratory rate_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0005573IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• abnormal heart right ventricle pressure_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0010755IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased erythrocyte cell number_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0003131IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• increased hemoglobin content_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0005564IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• thick ventricular wall_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0002953IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased circulating erythropoietin level_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0011285IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased erythrocyte cell number_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0003131IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• pulmonary artery hypoplasia_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0010460IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased heart weight_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0002833IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased monocyte cell number_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0000220IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl
• increased lymphocyte cell number_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0005013IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• increased leukocyte cell number_Epas1<tm1.1Fsl>/Epas1<+>
  http://metadb.riken.jp/0000218IC57BL6C57BL6NTacEpas1tm11FslEpas1Epas1tm11FslEpas1
• increased spleen weight_Epas1<tm1.1Fsl>/Epas1<tm1.1Fsl>
  http://metadb.riken.jp/0004952IC57BL6C57BL6NTacEpas1tm11FslEpas1tm11FslEpas1tm11Fsl