Ying. Jiang, et.al., Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells., The Journal of biological chemistry, 2013, 288

http://rdf.ncbi.nlm.nih.gov/pubmed/23649630

Ying. Jiang, et.al., Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells., The Journal of biological chemistry, 2013, 288

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sox11<tm1.1Gan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5518640

class

http://purl.org/net/cito/citesAsAuthority

• Sox11<tm1.1Gan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5518640

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased retinal apoptosis_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0030005I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• abnormal retina morphology_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0001325I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• decreased retinal ganglion cell number_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006309I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• abnormal retinal bipolar cell morphology_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006073I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• abnormal retinal bipolar cell morphology_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006073I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• abnormal retina morphology_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0001325I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• decreased retinal ganglion cell number_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006309I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• decreased amacrine cell number_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008106I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• absent optic nerve_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0001333I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• thin retinal inner nuclear layer_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008511I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• absent retinal inner plexiform layer_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008514I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• absent retinal ganglion cell_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008068I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• abnormal eye development_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0001286I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• optic nerve hypoplasia_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006221I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• thin retinal ganglion layer_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008507I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• abnormal axon fasciculation_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0009450I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• decreased amacrine cell number_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008106I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• abnormal axon fasciculation_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0009450I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• optic nerve hypoplasia_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006221I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• thin retinal inner nuclear layer_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008511I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• thin retinal ganglion layer_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008507I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• decreased birth weight_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0009674I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• absent retinal ganglion layer_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008510I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• increased retinal apoptosis_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0030005I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• decreased amacrine cell number_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008106I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• abnormal eye development_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0001286I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• increased retinal apoptosis_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0030005I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• decreased birth body size_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0009703I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• postnatal lethality, complete penetrance_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0011085I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• abnormal retinal outer plexiform layer morphology_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0003732I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• thin retinal ganglion layer_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0008507I129S6SvEvTacC57BL6C57BL6JDBA2Sox11tm11GanSox11tm11GanTgSix3cre69Frty0TgSix3cre69FrtySox11tm11Gan
• decreased retinal ganglion cell number_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006309I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty
• abnormal eye development_Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0001286I129S1Sv129X1SvJC57BL6C57BL6JDBA2Sox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox4tm1VlfTgSix3cre69Frty
• abnormal retinal bipolar cell morphology_Sox11<tm1.1Gan>/Sox11<tm1.1Gan>,Sox4<tm1Vlf>/Sox4<tm1Vlf>,Tg(Six3-cre)69Frty/0
  http://metadb.riken.jp/0006073I129S1Sv129S6SvEvTac129X1SvJC57BL6DBA2Sox11tm11GanSox11tm11GanSox4tm1VlfSox4tm1VlfTgSix3cre69Frty0Sox11tm11GanSox4tm1VlfTgSix3cre69Frty