Mikael. Bjursell, et.al., Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH., PloS one, 2013, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/23700488

Mikael. Bjursell, et.al., Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH., PloS one, 2013, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5521510

class

http://purl.org/net/cito/citesAsAuthority

• Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5521510

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0000063B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• abnormal liver physiology_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0000609B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• jaundice_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0000611B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased body weight_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0001262B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• liver inflammation_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0001860B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• hepatic steatosis_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0002628B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
他25件を見る
• decreased circulating free fatty acid level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0002702B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased circulating insulin level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0002727B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased circulating alanine transaminase level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0002941B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased liver weight_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0002981B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• liver degeneration_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0003103B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased bile salt level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0004789B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased energy expenditure_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0004889B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased spleen weight_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0004952B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased circulating cholesterol level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0005178B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• impaired glucose tolerance_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0005293B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased circulating bilirubin level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0005344B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased circulating glucose level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0005560B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• abnormal liver perisinusoidal space morphology_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0008988B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• abnormal liver sinusoid morphology_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0008989B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased white fat cell size_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009133B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased epididymal fat pad weight_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009289B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased interscapular fat pad weight_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009295B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased retroperitoneal fat pad weight_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009305B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• enlarged gallbladder_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009342B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased liver triglyceride level_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009355B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• enlarged cecum_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0009476B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased total body fat amount_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0010025B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• decreased bone mineral content_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0010124B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased food intake_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0011939B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj
• increased fluid intake_Nr1h4<tm1.1Mbj>/Nr1h4<tm1.1Mbj>
  http://metadb.riken.jp/0011941B6NB6Nr1h4tm11MbjNr1h4tm11MbjNr1h4tm11MbjNr1h4tm11Mbj