K E. Christensen, et.al., A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development., Human molecular genetics, 2013, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23704330

K E. Christensen, et.al., A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development., Human molecular genetics, 2013, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5521203

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased leukocyte cell number_Mthfd1<tm1.1Rzn>/Mthfd1<+>
  http://metadb.riken.jp/0000221I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1Mthfd1Mthfd1tm11Rzn
• abnormal folic acid level_Mthfd1<tm1.1Rzn>/Mthfd1<+>
  http://metadb.riken.jp/0011230I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1Mthfd1Mthfd1tm11Rzn
• preweaning lethality, complete penetrance_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0011100B6N129Mthfd1tm11RznMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• decreased embryo size_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0001698I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• maternal effect_Mthfd1<tm1.1Rzn>/Mthfd1<+>
  http://metadb.riken.jp/0003718I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1Mthfd1Mthfd1tm11Rzn
• small tail bud_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0012062I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• open neural tube_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0000929I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• embryonic growth retardation_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0003984I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• abnormal neural tube closure_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0003720I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• kinked neural tube_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0003400I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• wavy neural tube_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0000930I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• abnormal cell physiology_Mthfd1<tm1.1Rzn>/Mthfd1<+>
  http://metadb.riken.jp/0005621I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1Mthfd1Mthfd1tm11Rzn
• impaired somite development_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0009768I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• absent somites_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0006386I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• decreased neutrophil cell number_Mthfd1<tm1.1Rzn>/Mthfd1<+>
  http://metadb.riken.jp/0000222I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1Mthfd1Mthfd1tm11Rzn
• embryonic lethality during organogenesis, complete penetrance_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• increased body weight_Mthfd1<tm1.1Rzn>/Mthfd1<+>
  http://metadb.riken.jp/0001260I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1Mthfd1Mthfd1tm11Rzn
• abnormal tail bud morphology_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0002861I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn
• abnormal heart morphology_Mthfd1<tm1.1Rzn>/Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/0000266I129S1Sv129X1SvJC57BL6NMthfd1tm11RznMthfd1tm11RznMthfd1tm11Rzn

class

http://purl.org/net/cito/citesAsAuthority

• Mthfd1<tm1.1Rzn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5521203