Dawei. Jiang, et.al., Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/23716663

Dawei. Jiang, et.al., Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Letm1<Gt(CC0204)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3870303
• Letm1<Gt(DD0926)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3871268

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mitochondrial physiology_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0006036129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• abnormal brain morphology_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002152129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• abnormal amino acid metabolism_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0013242129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• embryonic lethality during organogenesis, incomplete penetrance_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0011108129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• decreased embryo size_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0001698129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• abnormal liver physiology_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0000609129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal liver physiology_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0000609129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• abnormal enzyme/coenzyme activity_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0005584129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• decreased oxygen consumption_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0005290129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• decreased embryo size_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0001698129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• increased susceptibility to pharmacologically induced seizures_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002906129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• embryonic lethality, complete penetrance_Letm1<Gt(CC0204)Wtsi>/Letm1<Gt(CC0204)Wtsi>
  http://metadb.riken.jp/0011092129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1GtCC0204Wtsi
• embryonic lethality during organogenesis, incomplete penetrance_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0011108129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal embryo development_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0001672129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• abnormal mitochondrial physiology_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0006036129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal glucose homeostasis_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002078129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• decreased heart weight_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002834129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal brain morphology_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002152129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• increased susceptibility to pharmacologically induced seizures_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002906129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal enzyme/coenzyme activity_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0005584129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal embryo development_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0001672129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal amino acid metabolism_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0013242129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• abnormal glucose homeostasis_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002078129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• embryonic growth retardation_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0003984129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• embryonic lethality, complete penetrance_Letm1<Gt(DD0926)Wtsi>/Letm1<Gt(DD0926)Wtsi>
  http://metadb.riken.jp/0011092129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1GtDD0926Wtsi
• decreased heart weight_Letm1<Gt(DD0926)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0002834129S129P2Letm1GtDD0926WtsiLetm1GtDD0926WtsiLetm1Letm1Letm1GtDD0926Wtsi
• embryonic growth retardation_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0003984129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1
• decreased oxygen consumption_Letm1<Gt(CC0204)Wtsi>/Letm1<+>
  http://metadb.riken.jp/0005290129S129P2Letm1GtCC0204WtsiLetm1GtCC0204WtsiLetm1Letm1GtCC0204WtsiLetm1

class

http://purl.org/net/cito/citesAsAuthority

• Letm1<Gt(CC0204)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3870303
• Letm1<Gt(DD0926)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3871268