Iva. Simeonova, et.al., Mutant mice lacking the p53 C-terminal domain model telomere syndromes., Cell reports, 2013, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/23770245

Iva. Simeonova, et.al., Mutant mice lacking the p53 C-terminal domain model telomere syndromes., Cell reports, 2013, 3

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm2Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523993
• Trp53<tm1.1Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523909
• Trp53<tm1Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523907
• Trp53<tm2.1Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523990

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal lethality, incomplete penetrance_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0011086I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• decreased bone marrow cell number_Mdm2<tm1Glo>/Mdm2<+>,Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0000333I129S2SvPas129S7SvEvBrdBALBcC57BL6Mdm2tm1GloMdm2Trp53tm11TldoTrp53Mdm2Trp53tm11TldoTrp53Mdm2tm1Glo
• cerebellum hypoplasia_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0000851I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• increased foot pad pigmentation_Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0000575I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53Trp53tm11TldoTrp53
• premature death_Mdm2<tm1Glo>/Mdm2<+>,Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPas129S7SvEvBrdBALBcC57BL6Mdm2tm1GloMdm2Trp53tm11TldoTrp53Mdm2Trp53tm11TldoTrp53Mdm2tm1Glo
• decreased body size_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0001265I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• premature death_Mdm4<tm1Glo>/Mdm4<+>,Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPasBALBcC57BL6Mdm4tm1GloMdm4Trp53tm11TldoTrp53Mdm4Trp53Mdm4tm1GloTrp53tm11Tldo
• increased tail pigmentation_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0011276I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• decreased bone marrow cell number_Mdm4<tm1Glo>/Mdm4<+>,Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0000333I129S2SvPasBALBcC57BL6Mdm4tm1GloMdm4Trp53tm11TldoTrp53Mdm4Trp53Mdm4tm1GloTrp53tm11Tldo
• nail dystrophy_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0012400I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• increased foot pad pigmentation_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0000575I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• abnormal telomere length_Mdm2<tm1Glo>/Mdm2<+>,Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0003155I129S2SvPas129S7SvEvBrdBALBcC57BL6Mdm2tm1GloMdm2Trp53tm11TldoTrp53Mdm2Trp53tm11TldoTrp53Mdm2tm1Glo
• oral leukoplakia_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0003751I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• premature death_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0002083I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• abnormal telomere length_Mdm4<tm1Glo>/Mdm4<+>,Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0003155I129S2SvPasBALBcC57BL6Mdm4tm1GloMdm4Trp53tm11TldoTrp53Mdm4Trp53Mdm4tm1GloTrp53tm11Tldo
• increased tail pigmentation_Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0011276I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53Trp53tm11TldoTrp53
• pulmonary fibrosis_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0006050I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• abnormal tongue morphology_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0000762I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• cardiac hypertrophy_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0001625I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• small gonad_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0001116I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• decreased bone marrow cell number_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0000333I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• abnormal telomere length_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0003155I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• cardiac hypertrophy_Trp53<tm1.1Tldo>/Trp53<+>
  http://metadb.riken.jp/0001625I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53Trp53tm11TldoTrp53
• pancytopenia_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0005152I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo
• increased thymocyte apoptosis_Trp53<tm1.1Tldo>/Trp53<tm1.1Tldo>
  http://metadb.riken.jp/0009541I129S2SvPasBALBcC57BL6Trp53tm11TldoTrp53tm11TldoTrp53tm11Tldo

class

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm2Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523993
• Trp53<tm1.1Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523909
• Trp53<tm1Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523907
• Trp53<tm2.1Tldo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523990