Simon. Verheijden, et.al., Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation., Neurobiology of disease, 2013, 58

http://rdf.ncbi.nlm.nih.gov/pubmed/23777740

Simon. Verheijden, et.al., Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation., Neurobiology of disease, 2013, 58

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hsd17b4<tm2Baes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523923

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tremors_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000745I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• tremors_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0000745I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• Purkinje cell degeneration_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000876I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• Purkinje cell degeneration_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0000876I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• demyelination_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000921I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• decreased body weight_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
他27件を見る
• increased anxiety-related response_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001363I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• increased anxiety-related response_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0001363I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• ataxia_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001393I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• ataxia_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0001393I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• impaired coordination_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001405I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• impaired coordination_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0001405I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• abnormal gait_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001406I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• abnormal gait_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0001406I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• short stride length_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001407I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• postnatal growth retardation_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001732I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• reduced female fertility_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001923I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• male infertility_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001925I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• decreased litter size_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001935I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• premature death_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• premature death_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• no abnormal phenotype detected_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>
  http://metadb.riken.jp/0002169I129C57BL6Hsd17b4tm2BaesHsd17b4tm2BaesHsd17b4tm2Baes
• neuron degeneration_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003224I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• astrocytosis_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0003354I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• lethargy_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0005202I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• increased fatty acid level_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005281I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• increased fatty acid level_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0005281I129S1Sv129X1SvJC57BL6Hsd17b4tm2BaesHsd17b4tm2BaesCnptm1creKanCnpCnpCnptm1creKanHsd17b4tm2Baes
• increased fatty acid level_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0005281I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• axon degeneration_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005405I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• axon degeneration_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0005405I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• microgliosis_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008918I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln
• microgliosis_Hsd17b4<tm1Baes>/Hsd17b4<tm1Baes>
  http://metadb.riken.jp/0008918I129S1Sv129X1SvJHsd17b4tm1BaesHsd17b4tm1BaesHsd17b4tm1Baes
• cerebellum atrophy_Hsd17b4<tm2Baes>/Hsd17b4<tm2Baes>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0014185I129C57BL6SJLHsd17b4tm2BaesHsd17b4tm2BaesTgNescre1Kln0Hsd17b4tm2BaesTgNescre1Kln

class

http://purl.org/net/cito/citesAsAuthority

• Hsd17b4<tm2Baes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523923