Sibylle. Sabrautzki, et.al., An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease., The American journal of pathology, 2013, 183

http://rdf.ncbi.nlm.nih.gov/pubmed/23791841

Sibylle. Sabrautzki, et.al., An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease., The American journal of pathology, 2013, 183

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Jak1<M1Mhda>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526094

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating cholesterol level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005179C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased IgA level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002495C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• thrombocytopenia_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0003179C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal glomerular mesangium morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0011339C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• anisocytosis_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002642C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased body weight_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0001262C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased IgG1 level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008499C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• hypoglycemia_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000189C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased liver regeneration_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005516C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal outer ear morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002177C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased birth body size_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0009703C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased plasma cell number_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008097C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal liver morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000598C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased urine urea nitrogen level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0011467C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• microcytic anemia_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002810C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased circulating serum albumin level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005419C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• skin inflammation_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0004947C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal circulating creatinine level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005328C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased bone trabecula number_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0010869C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased compact bone volume_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0010965C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• skin lesions_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0001212C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased mean platelet volume_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008935C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased mean corpuscular volume_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002591C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• enlarged spleen_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000691C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal dermal layer morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0001243C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased erythrocyte cell number_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0003131C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased immunoglobulin level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002461C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased megakaryocyte cell number_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008255C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• liver hyperplasia_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005141C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased circulating calcium level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000194C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• enlarged liver sinusoidal spaces_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000602C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• alopecia_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000414C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased circulating total protein level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005567C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased anti-nuclear antigen antibody level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0004794C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased blood uric acid level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008821C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased alkaline phosphatase activity_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0011584C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal liver vasculature morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0009820C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased circulating phosphate level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000198C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased IgG2a level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008500C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased cellular hemoglobin content_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0008956C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased circulating parathyroid hormone level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002905C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal compact bone morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0003797C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• ear inflammation_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0001849C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal bone trabecula morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0010867C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal bone resorption_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0004945C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• increased IgM level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002494C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased triglyceride level_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0005318C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal hepatocyte morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000607C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal plasma cell morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002439C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• decreased bone mineral density_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0000063C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1
• abnormal tail morphology_Jak1<M1Mhda>/Jak1<+>
  http://metadb.riken.jp/0002111C3HeBFeJJak1M1MhdaJak1M1MhdaJak1Jak1M1MhdaJak1

class

http://purl.org/net/cito/citesAsAuthority

• Jak1<M1Mhda>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526094