Cyril. Cheret, et.al., Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles., The EMBO journal, 2013, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/23792428

Cyril. Cheret, et.al., Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles., The EMBO journal, 2013, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nrg1<tm4Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524247
• Nrg1<tm4.1Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524248

class

http://purl.org/net/cito/citesAsAuthority

• Nrg1<tm4Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524247
• Nrg1<tm4.1Cbm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524248

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal gait_Nrg1<tm4Cbm>/Nrg1<tm4.1Cbm>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0001406I129P2OlaHsdBALBcJC57BL6JCBAJNrg1tm4CbmNrg1tm41CbmTgWnt1cre11Rth0TgWnt1cre11RthNrg1tm4CbmNrg1tm41Cbm
• decreased muscle spindle number_Bace1<tm1Psa>/Bace1<+>
  http://metadb.riken.jp/0008486I129S2SvPasC57BL6Bace1tm1PsaBace1Bace1Bace1tm1Psa
• abnormal muscle spindle morphology_Nrg1<tm4Cbm>/Nrg1<tm4.1Cbm>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0004069I129P2OlaHsdBALBcJC57BL6JCBAJNrg1tm4CbmNrg1tm41CbmTgWnt1cre11Rth0TgWnt1cre11RthNrg1tm4CbmNrg1tm41Cbm
• abnormal proprioceptive neuron morphology_Tg(Thy1-Nrg1*I)1Kan/0
  http://metadb.riken.jp/0004297I129P2OlaHsdC57BL6TgThy1Nrg1I1Kan0TgThy1Nrg1I1Kan
• abnormal muscle spindle morphology_Bace1<tm1Psa>/Bace1<tm1Psa>,Nrg1<tm4.1Cbm>/Nrg1<+>
  http://metadb.riken.jp/0004069I129P2OlaHsd129S2SvPasBALBcJC57BL6Bace1tm1PsaBace1tm1PsaNrg1tm41CbmNrg1Bace1tm1PsaNrg1Nrg1tm41Cbm
• impaired coordination_Bace1<tm1Psa>/Bace1<tm1Psa>
  http://metadb.riken.jp/0001405I129S2SvPasC57BL6Bace1tm1PsaBace1tm1PsaBace1tm1Psa
• increased muscle spindle number_Tg(Thy1-Nrg1*I)1Kan/0
  http://metadb.riken.jp/0008485I129P2OlaHsdC57BL6TgThy1Nrg1I1Kan0TgThy1Nrg1I1Kan
• abnormal muscle spindle morphology_Bace1<tm1Psa>/Bace1<tm1Psa>
  http://metadb.riken.jp/0004069I129S2SvPasC57BL6Bace1tm1PsaBace1tm1PsaBace1tm1Psa
• abnormal muscle spindle morphology_Nrg1<tm3Cbm>/Nrg1<tm3Cbm>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0004069I129P2OlaHsdC57BL6CBANrg1tm3CbmNrg1tm3CbmTgCAGcreEsr15Amc0TgCAGcreEsr15AmcNrg1tm3Cbm
• impaired coordination_Nrg1<tm3Cbm>/Nrg1<tm3Cbm>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001405I129P2OlaHsdC57BL6CBANrg1tm3CbmNrg1tm3CbmTgCAGcreEsr15Amc0TgCAGcreEsr15AmcNrg1tm3Cbm
• decreased muscle spindle number_Nrg1<tm4.1Cbm>/Nrg1<+>
  http://metadb.riken.jp/0008486I129P2OlaHsdBALBcJC57BL6Nrg1tm41CbmNrg1Nrg1tm41CbmNrg1
• demyelination_Egr2<tm2(cre)Pch>/Egr2<+>,Erbb2<tm2Cbm>/Erbb2<tm2Cbm>
  http://metadb.riken.jp/0000921I129P2OlaHsd129S2SvPasC57BL6Egr2tm2crePchEgr2Erbb2tm2CbmErbb2tm2CbmErbb2tm2CbmEgr2tm2crePchEgr2
• decreased muscle spindle number_Bace1<tm1Psa>/Bace1<tm1Psa>,Nrg1<tm4.1Cbm>/Nrg1<+>
  http://metadb.riken.jp/0008486I129P2OlaHsd129S2SvPasBALBcJC57BL6Bace1tm1PsaBace1tm1PsaNrg1tm41CbmNrg1Bace1tm1PsaNrg1Nrg1tm41Cbm
• abnormal muscle spindle morphology_Tg(Thy1-Nrg1*I)1Kan/0
  http://metadb.riken.jp/0004069I129P2OlaHsdC57BL6TgThy1Nrg1I1Kan0TgThy1Nrg1I1Kan
• decreased muscle spindle number_Bace1<tm1Psa>/Bace1<tm1Psa>,Tg(Thy1-Nrg1*I)1Kan/0
  http://metadb.riken.jp/0008486I129P2OlaHsd129S2SvPasC57BL6Bace1tm1PsaBace1tm1PsaTgThy1Nrg1I1Kan0TgThy1Nrg1I1KanBace1tm1Psa
• demyelination_Bace1<tm1Psa>/Bace1<tm1Psa>
  http://metadb.riken.jp/0000921I129S2SvPasC57BL6Bace1tm1PsaBace1tm1PsaBace1tm1Psa
• abnormal gait_Bace1<tm1Psa>/Bace1<tm1Psa>
  http://metadb.riken.jp/0001406I129S2SvPasC57BL6Bace1tm1PsaBace1tm1PsaBace1tm1Psa
• decreased muscle spindle number_Nrg1<tm3Cbm>/Nrg1<tm3Cbm>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008486I129P2OlaHsdC57BL6CBANrg1tm3CbmNrg1tm3CbmTgCAGcreEsr15Amc0TgCAGcreEsr15AmcNrg1tm3Cbm
• impaired coordination_Nrg1<tm4Cbm>/Nrg1<tm4.1Cbm>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0001405I129P2OlaHsdBALBcJC57BL6JCBAJNrg1tm4CbmNrg1tm41CbmTgWnt1cre11Rth0TgWnt1cre11RthNrg1tm4CbmNrg1tm41Cbm
• decreased muscle spindle number_Bace1<tm1Psa>/Bace1<tm1Psa>
  http://metadb.riken.jp/0008486I129S2SvPasC57BL6Bace1tm1PsaBace1tm1PsaBace1tm1Psa
• decreased muscle spindle number_Nrg1<tm4Cbm>/Nrg1<tm4.1Cbm>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008486I129P2OlaHsdBALBcJC57BL6JCBAJNrg1tm4CbmNrg1tm41CbmTgWnt1cre11Rth0TgWnt1cre11RthNrg1tm4CbmNrg1tm41Cbm