Rachel. Larder, et.al., Gene dosage of Otx2 is important for fertility in male mice., Molecular and cellular endocrinology, 2013, 377

http://rdf.ncbi.nlm.nih.gov/pubmed/23811236

Rachel. Larder, et.al., Gene dosage of Otx2 is important for fertility in male mice., Molecular and cellular endocrinology, 2013, 377

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• preweaning lethality, incomplete penetrance_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0011110IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2
• decreased testis weight_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0004852IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2
• decreased circulating luteinizing hormone level_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0002773IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2
• decreased litter size_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0001935IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2
• reduced male fertility_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0001922IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2
• abnormal gonadotroph morphology_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0008325IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2
• decreased gonadotroph cell number_Otx2<tm1Pas>/Otx2<+>
  http://metadb.riken.jp/0008335IC57BL6FVBNOtx2tm1PasOtx2Otx2tm1PasOtx2