Hao. Chen, et.al., Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/23812757

Hao. Chen, et.al., Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gdf2<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5703975
• Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5703977

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal vitelline vascular remodeling_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0004076I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• heart hypoplasia_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0002740C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• decreased fetal cardiomyocyte proliferation_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0011395C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• arteriovenous malformation_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0006093I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• enlarged heart_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0000274C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• abnormal vascular development_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0000259I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• hydrops fetalis_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0002192C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• thin ventricular wall_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0000280C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• abnormal retinal vasculature morphology_Gdf2<tm1Lex>/Gdf2<tm1Lex>
  http://metadb.riken.jp/0002792I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2tm1LexGdf2tm1Lex
• dilated dorsal aorta_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0004068I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• hemorrhage_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0001914C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• lethality throughout fetal growth and development, complete penetrance_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0011099C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• abnormal heart shape_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0000277C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• ventricular septal defect_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0010402C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• abnormal heart development_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0000267C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• enlarged pericardium_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0000291I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• lymphangiectasis_Gdf2<tm1Lex>/Gdf2<tm1Lex>
  http://metadb.riken.jp/0004038I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2tm1LexGdf2tm1Lex
• absent vitelline blood vessels_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0001719I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• abnormal heart morphology_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0000266C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• abnormal blood vessel morphology_Gdf2<tm1Lex>/Gdf2<tm1Lex>
  http://metadb.riken.jp/0001614I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2tm1LexGdf2tm1Lex
• decreased embryo size_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0001698I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• abnormal lymphatic vessel morphology_Gdf2<tm1Lex>/Gdf2<tm1Lex>
  http://metadb.riken.jp/0001879I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2tm1LexGdf2tm1Lex
• pericardial edema_Bmp10<tm1.1(Gdf2)Minh>/Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/0001787C57BL6NBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2MinhBmp10tm11Gdf2Minh
• abnormal retinal blood vessel morphology_Gdf2<tm1Lex>/Gdf2<tm1Lex>
  http://metadb.riken.jp/0010097I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2tm1LexGdf2tm1Lex
• abnormal retinal vasculature morphology_Gdf2<tm1Lex>/Gdf2<+>
  http://metadb.riken.jp/0002792I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2Gdf2tm1LexGdf2
• abnormal retinal blood vessel pattern_Gdf2<tm1Lex>/Gdf2<tm1Lex>
  http://metadb.riken.jp/0010098I129S5SvEvBrdC57BL6Gdf2tm1LexGdf2tm1LexGdf2tm1Lex
• embryonic growth arrest_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0001730I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou
• abnormal cardinal vein morphology_Bmp10<tm1Shou>/Bmp10<tm1Shou>
  http://metadb.riken.jp/0004783I129SSvEvBmp10tm1ShouBmp10tm1ShouBmp10tm1Shou

class

http://purl.org/net/cito/citesAsAuthority

• Gdf2<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5703975
• Bmp10<tm1.1(Gdf2)Minh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5703977