Yao. Chen, et.al., Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10., Journal of immunology (Baltimore, Md. : 1950), 2013, 191

http://rdf.ncbi.nlm.nih.gov/pubmed/23825311

Yao. Chen, et.al., Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10., Journal of immunology (Baltimore, Md. : 1950), 2013, 191

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Igh-J<tm3.1(48d)Lave>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550247
• Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550246
• Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550248

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal B cell differentiation_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0002144IC57BL6IghJtm214E10LaveIghJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIghJtm214E10Lave
• decreased B-1a cell number_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0008168IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• abnormal B cell differentiation_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>
  http://metadb.riken.jp/0002144NSIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveIgkJtm11LaveIghJtm11Lave
• abnormal B cell physiology_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0002459IC57BL6IghJtm214E10LaveIghJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIghJtm214E10Lave
• arrested B cell differentiation_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>
  http://metadb.riken.jp/0001802NSIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveIgkJtm11LaveIghJtm11Lave
• decreased immature B cell number_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0008215IC57BL6IghJtm214E10LaveIghJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIghJtm214E10Lave
• decreased IgG1 level_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0008495IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• decreased mature B cell number_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>
  http://metadb.riken.jp/0008211NSIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveIgkJtm11LaveIghJtm11Lave
• decreased IgM level_Igh-J<tm3.1(48d)Lave>/Igh-J<tm3.1(48d)Lave>
  http://metadb.riken.jp/0001806IC57BL6IghJtm3148dLaveIghJtm3148dLaveIghJtm3148dLave
• arrested B cell differentiation_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0001802IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• arrested B cell differentiation_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0001802IC57BL6IghJtm214E10LaveIghJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIghJtm214E10Lave
• decreased IgG2b level_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0008497IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• decreased IgM level_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0001806IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• decreased IgG3 level_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0008498IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• decreased B-1a cell number_Igh-J<tm3.1(48d)Lave>/Igh-J<tm3.1(48d)Lave>
  http://metadb.riken.jp/0008168IC57BL6IghJtm3148dLaveIghJtm3148dLaveIghJtm3148dLave
• decreased IgG1 level_Igh-J<tm3.1(48d)Lave>/Igh-J<tm3.1(48d)Lave>
  http://metadb.riken.jp/0008495IC57BL6IghJtm3148dLaveIghJtm3148dLaveIghJtm3148dLave
• decreased B cell number_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>
  http://metadb.riken.jp/0005017NSIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveIgkJtm11LaveIghJtm11Lave
• decreased IgG level_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0001805IC57BL6IghJtm214E10LaveIghJtm214E10LaveIghJtm214E10Lave
• decreased immature B cell number_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>
  http://metadb.riken.jp/0008215NSIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveIgkJtm11LaveIghJtm11Lave
• abnormal B cell physiology_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>
  http://metadb.riken.jp/0002459NSIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveIgkJtm11LaveIghJtm11Lave
• decreased IgG2b level_Igh-J<tm3.1(48d)Lave>/Igh-J<tm3.1(48d)Lave>
  http://metadb.riken.jp/0008497IC57BL6IghJtm3148dLaveIghJtm3148dLaveIghJtm3148dLave
• decreased mature B cell number_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/0008211IC57BL6IghJtm214E10LaveIghJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIghJtm214E10Lave

class

http://purl.org/net/cito/citesAsAuthority

• Igh-J<tm3.1(48d)Lave>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550247
• Igh-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550246
• Igk-J<tm2.1(4E10)Lave>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550248