Michelle. Goldsworthy, et.al., Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice., PloS one, 2013, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/23826075

Michelle. Goldsworthy, et.al., Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice., PloS one, 2013, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kmt2b<m1H>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5532298

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart looping_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0000269IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• abnormal head morphology_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0000432IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• abnormal hepatocyte morphology_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0000607IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• exencephaly_Kmt2b<Gena263>/Kmt2b<tm1Afst>
  http://metadb.riken.jp/0000914I129P2OlaHsdBALBcC3HHeHKmt2bGena263Kmt2btm1AfstKmt2bGena263Kmt2btm1Afst
• exencephaly_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0000914IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• increased circulating triglyceride level_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0001552IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
他37件を見る
• abnormal embryo turning_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0001700IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• edema_Kmt2b<Gena263>/Kmt2b<tm1Afst>
  http://metadb.riken.jp/0001785I129P2OlaHsdBALBcC3HHeHKmt2bGena263Kmt2btm1AfstKmt2bGena263Kmt2btm1Afst
• increased circulating insulin level_Kmt2b<tm1Afst>/Kmt2b<+>
  http://metadb.riken.jp/0002079I129P2OlaHsdKmt2btm1AfstKmt2bKmt2btm1AfstKmt2b
• increased circulating insulin level_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0002079IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased circulating insulin level_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0002079IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• hepatic steatosis_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0002628IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased liver weight_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0002981IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased liver weight_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0002981IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• decreased insulin secretion_Kmt2b<tm1Afst>/Kmt2b<+>
  http://metadb.riken.jp/0003059I129P2OlaHsdKmt2btm1AfstKmt2bKmt2btm1AfstKmt2b
• decreased insulin secretion_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0003059IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• decreased insulin secretion_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0003059IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• embryonic growth retardation_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0003984IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• increased circulating cholesterol level_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0005178IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• impaired glucose tolerance_Kmt2b<tm1Afst>/Kmt2b<+>
  http://metadb.riken.jp/0005293I129P2OlaHsdKmt2btm1AfstKmt2bKmt2btm1AfstKmt2b
• impaired glucose tolerance_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0005293IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• impaired glucose tolerance_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0005293IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• pericardial effusion_Kmt2b<Gena263>/Kmt2b<tm1Afst>
  http://metadb.riken.jp/0005312I129P2OlaHsdBALBcC3HHeHKmt2bGena263Kmt2btm1AfstKmt2bGena263Kmt2btm1Afst
• pericardial effusion_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0005312IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• insulin resistance_Kmt2b<tm1Afst>/Kmt2b<+>
  http://metadb.riken.jp/0005331I129P2OlaHsdKmt2btm1AfstKmt2bKmt2btm1AfstKmt2b
• insulin resistance_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0005331IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• insulin resistance_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0005331IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• increased circulating glucose level_Kmt2b<tm1Afst>/Kmt2b<+>
  http://metadb.riken.jp/0005559I129P2OlaHsdKmt2btm1AfstKmt2bKmt2btm1AfstKmt2b
• increased circulating glucose level_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0005559IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased circulating glucose level_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0005559IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• enlarged pancreatic islets_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0009171IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased epididymal fat pad weight_Kmt2b<tm1Afst>/Kmt2b<+>
  http://metadb.riken.jp/0009288I129P2OlaHsdKmt2btm1AfstKmt2bKmt2btm1AfstKmt2b
• decreased epididymal fat pad weight_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0009289IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• decreased epididymal fat pad weight_Kmt2b<m1H>/Kmt2b<+>
  http://metadb.riken.jp/0009289IBALBcC3HHeHKmt2bm1HKmt2bKmt2bKmt2bm1H
• increased liver triglyceride level_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0009355IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased total body fat amount_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0010024IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• increased liver free fatty acids level_Kmt2b<Gena263>/Kmt2b<+>
  http://metadb.riken.jp/0010359IBALBcC3HHeHKmt2bGena263Kmt2bKmt2bGena263Kmt2b
• perinatal lethality, complete penetrance_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0011089IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• embryonic lethality during organogenesis, complete penetrance_Kmt2b<Gena263>/Kmt2b<tm1Afst>
  http://metadb.riken.jp/0011098I129P2OlaHsdBALBcC3HHeHKmt2bGena263Kmt2btm1AfstKmt2bGena263Kmt2btm1Afst
• embryonic lethality, incomplete penetrance_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0011102IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• embryonic lethality between somite formation and embryo turning, incomplete penetrance_Kmt2b<Gena263>/Kmt2b<tm1Afst>
  http://metadb.riken.jp/0011107I129P2OlaHsdBALBcC3HHeHKmt2bGena263Kmt2btm1AfstKmt2bGena263Kmt2btm1Afst
• lethality during fetal growth through weaning, incomplete penetrance_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0011112IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263
• rostral body truncation_Kmt2b<Gena263>/Kmt2b<Gena263>
  http://metadb.riken.jp/0012157IBALBcC3HHeHKmt2bGena263Kmt2bGena263Kmt2bGena263

class

http://purl.org/net/cito/citesAsAuthority

• Kmt2b<m1H>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5532298