Natalia. Ramos-Hernández, et.al., Ndfip1 enforces a requirement for CD28 costimulation by limiting IL-2 production., Journal of immunology (Baltimore, Md. : 1950), 2013, 191

http://rdf.ncbi.nlm.nih.gov/pubmed/23851689

Natalia. Ramos-Hernández, et.al., Ndfip1 enforces a requirement for CD28 costimulation by limiting IL-2 production., Journal of immunology (Baltimore, Md. : 1950), 2013, 191

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ndfip1<tm1.1Pmo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550254

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• esophageal inflammation_Cd28<tm1Mak>/Cd28<tm1Mak>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0003278I129P2OlaHsd129S2SvPasCd28tm1MakCd28tm1MakNdfip1GtRRD002BygNdfip1GtRRD002BygCd28tm1MakNdfip1GtRRD002Byg
• lung inflammation_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0001861I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• esophageal inflammation_Ndfip1<tm1.1Pmo>/Ndfip1<tm1.1Pmo>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0003278IC57BL6DBA2Ndfip1tm11PmoNdfip1tm11PmoTgCd4cre1Cwi0Ndfip1tm11PmoTgCd4cre1Cwi
• esophageal inflammation_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0003278I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• increased T cell proliferation_Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0005348I129P2OlaHsdNdfip1GtRRD002BygNdfip1GtRRD002BygNdfip1GtRRD002Byg
• abnormal T cell physiology_Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0002444I129P2OlaHsdNdfip1GtRRD002BygNdfip1GtRRD002BygNdfip1GtRRD002Byg
• increased interleukin-4 secretion_Cd28<tm1Mak>/Cd28<tm1Mak>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0008699I129P2OlaHsd129S2SvPasCd28tm1MakCd28tm1MakNdfip1GtRRD002BygNdfip1GtRRD002BygCd28tm1MakNdfip1GtRRD002Byg
• increased eosinophil cell number_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0005011I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• premature death_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0002083I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• increased inflammatory response_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0001846I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• increased interleukin-2 secretion_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0008687I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• increased activated T cell number_Ndfip1<tm1.1Pmo>/Ndfip1<tm1.1Pmo>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001829IC57BL6DBA2Ndfip1tm11PmoNdfip1tm11PmoTgCd4cre1Cwi0Ndfip1tm11PmoTgCd4cre1Cwi
• skin inflammation_Ndfip1<tm1.1Pmo>/Ndfip1<tm1.1Pmo>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0004947IC57BL6DBA2Ndfip1tm11PmoNdfip1tm11PmoTgCd4cre1Cwi0Ndfip1tm11PmoTgCd4cre1Cwi
• increased neutrophil cell number_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0000219I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• increased eosinophil cell number_Ndfip1<tm1.1Pmo>/Ndfip1<tm1.1Pmo>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005011IC57BL6DBA2Ndfip1tm11PmoNdfip1tm11PmoTgCd4cre1Cwi0Ndfip1tm11PmoTgCd4cre1Cwi
• increased interleukin-2 secretion_Cd28<tm1Mak>/Cd28<tm1Mak>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0008687I129P2OlaHsd129S2SvPasCd28tm1MakCd28tm1MakNdfip1GtRRD002BygNdfip1GtRRD002BygCd28tm1MakNdfip1GtRRD002Byg
• increased interleukin-2 secretion_Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0008687I129P2OlaHsdNdfip1GtRRD002BygNdfip1GtRRD002BygNdfip1GtRRD002Byg
• increased eosinophil cell number_Cd28<tm1Mak>/Cd28<tm1Mak>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0005011I129P2OlaHsd129S2SvPasCd28tm1MakCd28tm1MakNdfip1GtRRD002BygNdfip1GtRRD002BygCd28tm1MakNdfip1GtRRD002Byg
• increased T cell number_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0005015I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• abnormal esophageal epithelium morphology_Cd28<tm1Mak>/Cd28<tm1Mak>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0000468I129P2OlaHsd129S2SvPasCd28tm1MakCd28tm1MakNdfip1GtRRD002BygNdfip1GtRRD002BygCd28tm1MakNdfip1GtRRD002Byg
• increased activated T cell number_Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0001829I129P2OlaHsdNdfip1GtRRD002BygNdfip1GtRRD002BygNdfip1GtRRD002Byg
• lung epithelium hyperplasia_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0010945I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• increased CD4-positive, alpha beta T cell number_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0008074I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg
• esophageal epithelium hyperplasia_Il4<tm1Cgn>/Il4<tm1Cgn>,Ndfip1<Gt(RRD002)Byg>/Ndfip1<Gt(RRD002)Byg>
  http://metadb.riken.jp/0000466I129P2OlaHsdIl4tm1CgnIl4tm1CgnNdfip1GtRRD002BygNdfip1GtRRD002BygIl4tm1CgnNdfip1GtRRD002Byg

class

http://purl.org/net/cito/citesAsAuthority

• Ndfip1<tm1.1Pmo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5550254