Masato. Asai, et.al., Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity., Science (New York, N.Y.), 2013, 341

http://rdf.ncbi.nlm.nih.gov/pubmed/23869016

Masato. Asai, et.al., Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity., Science (New York, N.Y.), 2013, 341

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mrap2<tm1.2Maj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526064
• Mrap2<tm1Maj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526059
• Mrap2<tm1.1Maj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526063

class

http://purl.org/net/cito/citesAsAuthority

• Mrap2<tm1.2Maj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526064
• Mrap2<tm1Maj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526059
• Mrap2<tm1.1Maj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526063

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• polyphagia_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0001433EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• obese_Mrap2<tm1.2Maj>/Mrap2<tm1.2Maj>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0001261I129S6SvEvTac129X1SvJC57BL6FVBNMrap2tm12MajMrap2tm12MajTgSim1cre1Lowl0Mrap2tm12MajTgSim1cre1Lowl
• obese_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>,Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0001261I129S4SvJae129S6SvEvTacC57BL6Mc4rtm1LowlMc4rtm1LowlMrap2tm11MajMrap2tm11MajMrap2tm11MajMc4rtm1Lowl
• increased white fat cell size_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0009118EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• abnormal noradrenaline level_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0003964EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• abnormal circadian rhythm_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0001502EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• obese_Mc4r<tm1Lowl>/Mc4r<+>,Mrap2<tm1.1Maj>/Mrap2<+>
  http://metadb.riken.jp/0001261I129S4SvJae129S6SvEvTacC57BL6Mc4rtm1LowlMc4rMrap2tm11MajMrap2Mrap2Mrap2tm11MajMc4rtm1LowlMc4r
• obese_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0001261EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased total body fat amount_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0010024EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased percent body fat/body weight_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0005458EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased body length_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0001257EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• abnormal adrenaline level_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0003962EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• obese_Mc4r<tm1Lowl>/Mc4r<tm1Lowl>
  http://metadb.riken.jp/0001261I129S4SvJaeC57BL6JMc4rtm1LowlMc4rtm1LowlMc4rtm1Lowl
• increased body weight_Mrap2<tm1.1Maj>/Mrap2<+>
  http://metadb.riken.jp/0001260EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2Mrap2Mrap2tm11Maj
• decreased lean body mass_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0003961EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased susceptibility to weight gain_Mrap2<tm1.2Maj>/Mrap2<tm1.2Maj>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0005455I129S6SvEvTac129X1SvJC57BL6FVBNMrap2tm12MajMrap2tm12MajTgSim1cre1Lowl0Mrap2tm12MajTgSim1cre1Lowl
• hepatic steatosis_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0002628EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased susceptibility to weight gain_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0005455EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased circulating leptin level_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0005669EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• abnormal intestinal absorption_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0001666EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• obese_Mc4r<tm1Lowl>/Mc4r<+>
  http://metadb.riken.jp/0001261I129S4SvJaeC57BL6Mc4rtm1LowlMc4rMc4rMc4rtm1Lowl
• increased compensatory feeding amount_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0011958EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased brown adipose tissue amount_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0000005EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj
• increased food intake_Mrap2<tm1.1Maj>/Mrap2<tm1.1Maj>
  http://metadb.riken.jp/0011939EB6129Mrap2tm11MajorI129129S6SvEvTacMrap2tm11MajMrap2tm11MajMrap2tm11Maj