Jacqueline K. White, et.al., Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes., Cell, 2013, 154

http://rdf.ncbi.nlm.nih.gov/pubmed/23870131

Jacqueline K. White, et.al., Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes., Cell, 2013, 154

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• fused joints_Dnase1l2<tm1(KOMP)Wtsi>/Dnase1l2<tm1(KOMP)Wtsi>
  http://metadb.riken.jp/0003189IC57BL6NDnase1l2tm1KOMPWtsiDnase1l2tm1KOMPWtsiDnase1l2tm1KOMPWtsi
• enlarged lateral ventricles_Ap4e1<tm1a(KOMP)Wtsi>/Ap4e1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0008535IC57BL6NAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsi
• increased susceptibility to bacterial infection_Kptn<tm1a(EUCOMM)Wtsi>/Kptn<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002412IC57BL6NKptntm1aEUCOMMWtsiKptntm1aEUCOMMWtsiKptntm1aEUCOMMWtsi
• decreased grip strength_Dnase1l2<tm1(KOMP)Wtsi>/Dnase1l2<tm1(KOMP)Wtsi>
  http://metadb.riken.jp/0010053IC57BL6NDnase1l2tm1KOMPWtsiDnase1l2tm1KOMPWtsiDnase1l2tm1KOMPWtsi
• decreased lean body mass_Atp5a1<tm1a(EUCOMM)Wtsi>/Atp5a1<+>
  http://metadb.riken.jp/0003961IC57BL6NAtp5a1tm1aEUCOMMWtsiAtp5a1Atp5a1Atp5a1tm1aEUCOMMWtsi
• decreased vertical activity_Ap4e1<tm1a(KOMP)Wtsi>/Ap4e1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002757IC57BL6NAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsi
• impaired hearing_Fam107b<tm1a(KOMP)Wtsi>/Fam107b<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0006325IC57BL6NFam107btm1aKOMPWtsiFam107btm1aKOMPWtsiFam107btm1aKOMPWtsi
• edema_Mks1<tm1a(EUCOMM)Wtsi>/Mks1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001785IC57BL6NMks1tm1aEUCOMMWtsiMks1tm1aEUCOMMWtsiMks1tm1aEUCOMMWtsi
• embryonic lethality, complete penetrance_Smc3<tm1a(EUCOMM)Wtsi>/Smc3<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011092IC57BL6NSmc3tm1aEUCOMMWtsiSmc3tm1aEUCOMMWtsiSmc3tm1aEUCOMMWtsi
• decreased corpus callosum size_Ap4e1<tm1a(KOMP)Wtsi>/Ap4e1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0000781IC57BL6NAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsi
• increased body weight_Kptn<tm1a(EUCOMM)Wtsi>/Kptn<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001260IC57BL6NKptntm1aEUCOMMWtsiKptntm1aEUCOMMWtsiKptntm1aEUCOMMWtsi
• fetal growth retardation_Psat1<tm1a(KOMP)Wtsi>/Psat1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0004201IC57BL6NPsat1tm1aKOMPWtsiPsat1tm1aKOMPWtsiPsat1tm1aKOMPWtsi
• postnatal lethality, incomplete penetrance_Smc3<tm1a(EUCOMM)Wtsi>/Smc3<+>
  http://metadb.riken.jp/0011086IC57BL6NSmc3tm1aEUCOMMWtsiSmc3Smc3tm1aEUCOMMWtsiSmc3
• male infertility_Sms<tm1a(EUCOMM)Wtsi>/Y
  http://metadb.riken.jp/0001925IC57BL6NSmstm1aEUCOMMWtsiYSmstm1aEUCOMMWtsi
• hemorrhage_Sptbn1<tm1a(EUCOMM)Wtsi>/Sptbn1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001914IC57BL6NSptbn1tm1aEUCOMMWtsiSptbn1tm1aEUCOMMWtsiSptbn1tm1aEUCOMMWtsi
• eye opacity_Asxl1<tm1a(EUCOMM)Wtsi>/Asxl1<+>
  http://metadb.riken.jp/0009859IC57BL6NAsxl1tm1aEUCOMMWtsiAsxl1Asxl1Asxl1tm1aEUCOMMWtsi
• abnormal eye morphology_Mks1<tm1a(EUCOMM)Wtsi>/Mks1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002092IC57BL6NMks1tm1aEUCOMMWtsiMks1tm1aEUCOMMWtsiMks1tm1aEUCOMMWtsi
• lethality, complete penetrance_Asxl1<tm1a(EUCOMM)Wtsi>/Asxl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011400IC57BL6NAsxl1tm1aEUCOMMWtsiAsxl1tm1aEUCOMMWtsiAsxl1tm1aEUCOMMWtsi
• decreased lean body mass_Sms<tm1a(EUCOMM)Wtsi>/Y
  http://metadb.riken.jp/0003961IC57BL6NSmstm1aEUCOMMWtsiYSmstm1aEUCOMMWtsi
• abnormal craniofacial morphology_Psat1<tm1a(KOMP)Wtsi>/Psat1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0000428IC57BL6NPsat1tm1aKOMPWtsiPsat1tm1aKOMPWtsiPsat1tm1aKOMPWtsi
• increased T cell number_Smc3<tm1a(EUCOMM)Wtsi>/Smc3<+>
  http://metadb.riken.jp/0005015IC57BL6NSmc3tm1aEUCOMMWtsiSmc3Smc3tm1aEUCOMMWtsiSmc3
• decreased bone mineral density_Sms<tm1a(EUCOMM)Wtsi>/Y
  http://metadb.riken.jp/0000063IC57BL6NSmstm1aEUCOMMWtsiYSmstm1aEUCOMMWtsi
• small sebaceous gland_Cbx7<tm1a(KOMP)Wtsi>/Cbx7<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0012725IC57BL6NCbx7tm1aKOMPWtsiCbx7tm1aKOMPWtsiCbx7tm1aKOMPWtsi
• anemia_Ap4e1<tm1a(KOMP)Wtsi>/Ap4e1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001577IC57BL6NAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsiAp4e1tm1aKOMPWtsi
• polydactyly_Mks1<tm1a(EUCOMM)Wtsi>/Mks1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000562IC57BL6NMks1tm1aEUCOMMWtsiMks1tm1aEUCOMMWtsiMks1tm1aEUCOMMWtsi
• opacity of vitreous body_Asxl1<tm1a(EUCOMM)Wtsi>/Asxl1<+>
  http://metadb.riken.jp/0002700IC57BL6NAsxl1tm1aEUCOMMWtsiAsxl1Asxl1Asxl1tm1aEUCOMMWtsi
• exencephaly_Psat1<tm1a(KOMP)Wtsi>/Psat1<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0000914IC57BL6NPsat1tm1aKOMPWtsiPsat1tm1aKOMPWtsiPsat1tm1aKOMPWtsi
• muscle weakness_Sms<tm1a(EUCOMM)Wtsi>/Y
  http://metadb.riken.jp/0000747IC57BL6NSmstm1aEUCOMMWtsiYSmstm1aEUCOMMWtsi
• decreased lean body mass_Crlf3<tm1a(KOMP)Wtsi>/Crlf3<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0003961IC57BL6NCrlf3tm1aKOMPWtsiCrlf3tm1aKOMPWtsiCrlf3tm1aKOMPWtsi
• edema_Sptbn1<tm1a(EUCOMM)Wtsi>/Sptbn1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001785IC57BL6NSptbn1tm1aEUCOMMWtsiSptbn1tm1aEUCOMMWtsiSptbn1tm1aEUCOMMWtsi
• increased circulating magnesium level_Trmt10a<tm1a(EUCOMM)Wtsi>/Trmt10a<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0010092IC57BL6NTrmt10atm1aEUCOMMWtsiTrmt10atm1aEUCOMMWtsiTrmt10atm1aEUCOMMWtsi
• abnormal craniofacial morphology_Smc3<tm1a(EUCOMM)Wtsi>/Smc3<+>
  http://metadb.riken.jp/0000428IC57BL6NSmc3tm1aEUCOMMWtsiSmc3Smc3tm1aEUCOMMWtsiSmc3
• increased thermal nociceptive threshold_Git2<Gt(XG510)Byg>/Git2<Gt(XG510)Byg>
  http://metadb.riken.jp/0001973B6129P2Git2GtXG510BygGit2GtXG510BygGit2GtXG510BygGit2GtXG510Byg
• decreased body weight_Smc3<tm1a(EUCOMM)Wtsi>/Smc3<+>
  http://metadb.riken.jp/0001262IC57BL6NSmc3tm1aEUCOMMWtsiSmc3Smc3tm1aEUCOMMWtsiSmc3
• postnatal growth retardation_Sms<tm1a(EUCOMM)Wtsi>/Y
  http://metadb.riken.jp/0001732IC57BL6NSmstm1aEUCOMMWtsiYSmstm1aEUCOMMWtsi
• lordosis_Sms<tm1a(EUCOMM)Wtsi>/Y
  http://metadb.riken.jp/0000162IC57BL6NSmstm1aEUCOMMWtsiYSmstm1aEUCOMMWtsi