Mei. Xin, et.al., Hippo pathway effector Yap promotes cardiac regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/23918388

Mei. Xin, et.al., Hippo pathway effector Yap promotes cardiac regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Wwtr1<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544289
• Wwtr1<tm1.2Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544290
• Tg(Myh6-Yap1*S112A)#Eno
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544294

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart morphology_Wwtr1<tm1.1Eno>/Wwtr1<tm1.1Eno>,Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0000266I129SSvEvFVBNWwtr1tm11EnoWwtr1tm11EnoYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0TgMyh6cre2182MdsWwtr1tm11EnoYap1tm11Eno
• thin ventricular wall_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0000280I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• abnormal cardiovascular system physiology_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001544I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• abnormal cardiovascular system physiology_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0001544IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno
• abnormal atrial thrombosis_Wwtr1<tm1.1Eno>/Wwtr1<tm1.1Eno>,Yap1<tm1.1Eno>/Yap1<+>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001855I129SSvEvFVBNWwtr1tm11EnoWwtr1tm11EnoYap1tm11EnoYap1TgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsYap1
• abnormal atrial thrombosis_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001855I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
他22件を見る
• respiratory distress_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001954I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• premature death_Wwtr1<tm1.1Eno>/Wwtr1<tm1.1Eno>,Yap1<tm1.1Eno>/Yap1<+>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002083I129SSvEvFVBNWwtr1tm11EnoWwtr1tm11EnoYap1tm11EnoYap1TgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsYap1
• premature death_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002083I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• thin myocardium_Wwtr1<tm1.1Eno>/Wwtr1<+>,Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002652I129SSvEvFVBNWwtr1tm11EnoWwtr1Yap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsWwtr1
• dilated cardiomyopathy_Wwtr1<tm1.1Eno>/Wwtr1<tm1.1Eno>,Yap1<tm1.1Eno>/Yap1<+>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002795I129SSvEvFVBNWwtr1tm11EnoWwtr1tm11EnoYap1tm11EnoYap1TgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsYap1
• dilated cardiomyopathy_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002795I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• increased heart weight_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0002833IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno
• increased myocardial infarction size_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003037I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• decreased myocardial infarction size_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0003038IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno
• cardiac fibrosis_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003141I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• increased cardiomyocyte apoptosis_Wwtr1<tm1.1Eno>/Wwtr1<+>,Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003222I129SSvEvFVBNWwtr1tm11EnoWwtr1Yap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsWwtr1
• decreased cardiomyocyte apoptosis_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0003223IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno
• abnormal myocardial fiber physiology_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0004215IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno
• decreased cardiac muscle contractility_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005140I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• lethargy_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005202I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• dilated heart ventricle_Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0008022I129SSvEvFVBNYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoTgMyh6cre2182Mds
• polycystic kidney_Wwtr1<tm1.2Eno>/Wwtr1<tm1.2Eno>
  http://metadb.riken.jp/0008528I129SSvEvWwtr1tm12EnoWwtr1tm12EnoWwtr1tm12Eno
• myocardium hypoplasia_Wwtr1<tm1.1Eno>/Wwtr1<+>,Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0010500I129SSvEvFVBNWwtr1tm11EnoWwtr1Yap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsWwtr1
• thick myocardium_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0010656IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno
• postnatal lethality, complete penetrance_Wwtr1<tm1.1Eno>/Wwtr1<+>,Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0011085I129SSvEvFVBNWwtr1tm11EnoWwtr1Yap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0Yap1tm11EnoWwtr1tm11EnoTgMyh6cre2182MdsWwtr1
• neonatal lethality, complete penetrance_Wwtr1<tm1.1Eno>/Wwtr1<tm1.1Eno>,Yap1<tm1.1Eno>/Yap1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0011087I129SSvEvFVBNWwtr1tm11EnoWwtr1tm11EnoYap1tm11EnoYap1tm11EnoTgMyh6cre2182Mds0TgMyh6cre2182MdsWwtr1tm11EnoYap1tm11Eno
• abnormal cardiac muscle regeneration_Tg(Myh6-Yap1*S112A)#Eno/0
  http://metadb.riken.jp/0013238IC3HC57BL6TgMyh6Yap1S112AEno0TgMyh6Yap1S112AEno

class

http://purl.org/net/cito/citesAsAuthority

• Wwtr1<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544289
• Wwtr1<tm1.2Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544290
• Tg(Myh6-Yap1*S112A)#Eno
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544294